Structure

Tumor Antigens

Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates f...

Novartis

Novartis is the fourth largest pharmaceutical company in the world, based on annual sales, which are exceeded $36,000m in 2009. Founded in 1996, Novartis focuses of four main areas; pharmaceuticals,...

Bioscience - news, views, reports and blogs

Bioscience - any of the sciences that deal with living organisms.  The study of the nature, behavior, and uses of living organisms as applied to biology. Any of the branches of natural scienc...

PKC (Protein Kinase C)

PKC (protein kinase C) http://www.bioportfolio.com/channels/serine-threonine-protein-kinase-c-pkc is a kinase enzyme and a protein molecule that can change the format of other proteins through chemi...

Structure of the agonist-bound neurotensin receptor

The X-ray crystal structure of a rat neurotensin receptor in complex with the C-terminal portion of neurotensin is presented; this is the first structure of a member of the β group of class A G-prote...

Researchers determine structure of ‘batteries’ of the biological clock

Howard Hughes Medical Institute scientists have determined the three-dimensional structure of two proteins that help keep the body's clocks in sync. The proteins, CLOCK and BMAL1, bind to each other t...

Intrinsically disordered proteins: A conversation with Rohit Pappu

If you open any biology textbook to the section on proteins, you will learn that a protein is made up of a sequence of amino acids, that the sequence determines how the chain of amino acids folds into...

Atomic-scale determination of surface facets in gold nanorods

The atomic structure of nanoparticles considerably influences their properties. A new methodology that is now able to measure the full three-dimensional atomic structure of free-standing nanoparticles...

Internal bone structure reveals loading and walking behavior

The form and structure of bones change as a result of the forces to which they are subjected. Researchers have used this fact to determine the load using the bone structure. This knowledge can be impo...

New type of solar structure cools buildings in full sunlight

Homes and buildings chilled without air conditioners. Car interiors that don't heat up in the summer sun. Tapping the frigid expanses of outer space to cool the planet. Science fiction, you say? Well,...

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

Updated structure of Drosophila cryptochrome

Arising from B. D. Zoltowski et al.Nature480, 396–399 (2011)Recently, we determined the X-ray crystal structure of full-length cryptochrome from Drosophila. Here we report an improved model of the D...

Towards the discovery of a novel class of monoamine oxidase inhibitors: structure-property-activity and docking studies on chromone amides.

Diaminobenzenes: an experimental and computational study.

Experimental and Computational Thermochemical Study of α-Alanine (DL) and β-Alanine.

A Combined Experimental and Computational Thermodynamic Study of the Isomers of Pyrrolecarboxaldehyde and 1-Methyl- pyrrolecarboxaldehyde.

High-Accuracy Vapor Pressure Data of the Extended C(n)C(1)imNtf(2) Ionic Liquid Series: Trend Changes and Structural Shifts.