Search Results for "Ketofol Induction Agent Randomized Control Trial"
Original Source: A Comparison of Ketofol (Ketamine and Propofol Admixture) Versus Propofol as Induction Agents on Hemodynamic Parameters
This is a pilot study to compare the hemodynamic changes that occur during induction with a novel drug combination known as ketofol (propofol and ketamine admixture with that of propofol alone (prototypic anesthesia induction agent). Propofol and ketamine are widely used as induction agents and their effects on patient hemodynamics are well known. Some of these drug-induced hemodynamic changes are undesirable and lead to deleterious effects on patient hemodynamics. We seek t...
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Sustained high ventricular rates during persistent or permanent AF can lead to a deterioration in left ventricular function, hence the requirement for rate control. Historically, digoxin has been us...
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Haematological cancer: The rule of three in AML induction—is cladribine the answer?
In a randomized phase III trial of induction therapy in adult acute myeloid leukaemia, the addition of cladribine, but not fludarabine, to daunorubicin and cytarabine seemed to improve complete respon...
Combo Defeats Fungal Meningitis in HIV (CME/CE)
(MedPage Today) -- Induction therapy with combined amphotericin B and flucytosine improved survival in HIV-positive patients with cryptococcal meningitis, a randomized trial determined.
Acadesine Fails to Improve CABG Outcomes
Meta-analyses suggest that the adenosine-regulating agent acadesine could reduce important adverse events in coronary-bypass patients, so researchers compared the agent with placebo in a randomized tr...
ContextA large randomized controlled trial revealed that tight glucose control (TGC) to age-adjusted normoglycemia (50-80 mg/dL at age
Cinacalcet failure raises trial conduct issues
The oral calcimimetic agent, cinacalcet, has been found to have no significant effect on cardiovascular events or death in patients with chronic kidney disease in a randomized controlled trial.
ContextIschemia/reperfusion injury remains an important cause of morbidity and mortality after coronary artery bypass graft (CABG) surgery. In a meta-analysis of randomized controlled trials, perioper...
Topol: Get Rid of the Randomized Trial; Here's a Better Way
Dr. Eric Topol wants to throw out the 'contrived' randomized, placebo-controlled trial and launch the clinical trial of the future. Here's how he'd do it. Medscape
New Combination Sedative Ketofol Safer for Children
The newly-available combination of ketamine and propofol reduces adverse events in pediatric patients, report researchers. In another study, capnography during sedation led to fewer, but more appropri...
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Critically ill patients may require emergent intubations, and the use of some induction agents can lead to undesirable effects on hemodynamics. The use of "ketofol" (ketamine/propofol admixture) may a...
Ketofol in electroconvulsive therapy anesthesia: two stones for one bird.
PURPOSE: Propofol and ketamine have become progressively popular in electroconvulsive therapy (ECT) anesthesia, although propofol shortened seizure duration and ketamine might cause cardiotoxicity, ps...
Abstract Aims: To evaluate the efficacy of acupuncture, and sweeping of the fetal membranes, as methods for induction of labor. Methods: Four hundred and seven pregnant women with normal singleton pre...
Do messages of scarcity increase trial recruitment?
INTRODUCTION: Psychological theory suggests that participants may be more likely to volunteer to join a clinical trial if they perceive places in the trial are a scarce commodity. MATERIAL AND METHODS...
Attempting to compare the rates of premature luteinization (PL), clinical pregnancy, and cycle cancellation in ovulation induction-intrauterine insemination (OI-IUI) cycles with and without the GnRH a...
