Melanoma

Melanoma is a highly malignant tumor of melanin-forming cells (melanocytes) There are most commonly found in the skin (resulting from sunlight exposure), but also in the eyes and mucous membranes....

Lakes Dermatology Announces Allergan's New 5ml Latisse in Las Vegas, Nevada

Latisse is available in a larger size, which saves money for women who wish to grow their eyelashes longer and fuller. Las Vegas, NV (PRWEB) August 15, 2012 Lakes Dermatology Is offering Allergan'...

Syntaxin-3 Is Required for Melanosomal Localization of Tyrp1 in Melanocytes

Diacylglycerol Kinase Regulates Tyrosinase Expression and Function in Human Melanocytes

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

Melanocytes Derived from Transgene-Free Human Induced Pluripotent Stem Cells

Vitiligo-Inducing Phenols Activate the Unfolded Protein Response in Melanocytes Resulting in Upregulation of IL6 and IL8

Functional Melanocytes Are Readily Reprogrammable from Multilineage-Differentiating Stress-Enduring (Muse) Cells, Distinct Stem Cells in Human Fibroblasts

Linchpin of skin response to UVA light discovered

Researchers have strengthened their understanding of how skin cells called melanocytes sense ultraviolet light and act to protect themselves with melanin. In a new study, they report experiments showi...

Molecular and cellular pathogenesis of melanoma initiation and progression.

Melanoma is a malignant tumor of melanocytes that can spread to other organs of the body, resulting in severe and/or lethal malignancies. Melanocytes are pigment-producing cells found in the deep laye...

RNA released from necrotic keratinocytes upregulates intercellular adhesion molecule-1 expression in melanocytes.

Intercellular adhesion molecule-1 (ICAM-1) expression has been detected in melanocytes around active vitiligo patches as well as in surgically transplanted melanocytes. However, it is unclear whether...

Effect of Extracorporeal Shockwave Treatment on the Melanogenic Activity of Cultured Melanocytes.

In addition to the traditional lithotripsy treatment, extracorporeal shockwaves (ESWs) have been shown to be effective in the treatment of certain musculoskeletal disorders and in enhancing skin flap...

Co-culture of Melanocytes with Adipose-derived Stem Cells as a Potential Substitute for Co-culture with Keratinocytes.

Cell-to-cell interactions between melanocytes and keratinocytes increase the proliferation and migration of melanocytes. In fact, mixed keratinocyte and melanocyte cultures have been used for autologo...

Heme Oxygenase-1 Protects Human Melanocytes from H(2)O(2)-Induced Oxidative Stress via the Nrf2-ARE Pathway.

Oxidative stress caused by hydrogen peroxide (H(2)O(2)) leads to cell death and has been implicated in the pathogenesis of vitiligo. The nuclear factor E2-related factor 2 (Nrf2)-antioxidant response...