Refractory

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Neonatal infection

Refractory priapism

Refractory incontinence

Lyrica's New Role Could Pay Off Big For Pfizer Investors

ByStock Maelstrom:Pfizer (PFE) conducted an advanced study into the effects of its drug Lyrica, demonstrating that it is as effective as levetiracetam, Pfizer's own anti-seizure drug. Levetiracetam ha...

Pfizer's Lyrica equals levetiracetam in patients with partial onset seizures

Global pharma behemoth Pfizer (NYSE: PFE) has announced top-line results from a Phase III study showing its neuropathic pain drug Lyrica (pregabalin) controlled release was as effective as levetiracet...

Pfizer’s Lyrica meets goal in study of epilepsy seizures

Pfizer’s Lyrica (pregabalin) worked as well as the drug levetiracetam in reducing partial seizures among epilepsy patients in a study. The Phase III study met its primary goal of achieving at...

Human medicines European Public Assessment Report (EPAR): Levetiracetam Sun, levetiracetam, Revision: 1, Authorised

Human medicines European Public Assessment Report (EPAR): Levetiracetam Sun, levetiracetam, Revision: 2, Authorised

Human medicines European Public Assessment Report (EPAR): Levetiracetam Sun, levetiracetam, Revision: 3, Authorised

Human medicines European Public Assessment Report (EPAR): Levetiracetam Actavis, levetiracetam, Revision: 2, Authorised

Human medicines European Public Assessment Report (EPAR): Levetiracetam Accord, levetiracetam, Revision: 2, Authorised

Pregabalin or placebo used adjunctively with levetiracetam in refractory partial-onset epilepsy: a post hoc efficacy and safety analysis in combined clinical trials.

Abstract Objective: Some patients with epilepsy require treatment with >1 adjunctive antiepileptic drug (AED) to achieve adequate seizure remission. The purpose of this analysis was to evaluate the ef...

Effects of levetiracetam on blood-brain barrier disturbances following hyperthermia-induced seizures in rats with cortical dysplasia.

AIMS: The mechanisms underlying the changes in blood-brain barrier (BBB) integrity and the generation of seizures in childhood associated with preexisting brain lesions like cortical dysplasia (CD) ar...

Inhibitory effects of levetiracetam on absence seizures in a novel absence-like epilepsy animal model, Groggy rat.

Levetiracetam (LEV) is known to inhibit convulsive seizures and is clinically used for treating both partial and generalized seizures. The study was performed to determine whether LEV possesses an inh...

Treatment Options in Juvenile Myoclonic Epilepsy.

OPINION STATEMENT: Juvenile myoclonic epilepsy (JME) is characterized by excellent response to treatment, if diagnosed correctly. Lifestyle advice is an integral part of the treatment of JME; it shoul...

Levetiracetam in brain ischemia: Clinical implications in neuroprotection and prevention of post-stroke epilepsy.

Several new antiepileptic drugs (AEDs) have been introduced for clinical use recently. These new AEDs, like the classic AEDs, target multiple cellular sites both pre- and postsynaptically. The use of...