Search Results for "Liver Insufficiency After Chemotherapy"
Original Source: Chemotherapy, Liver Injury, and Postoperative Complications in Colorectal Liver Metastases.
BACKGROUND: Systemic chemotherapy (CTx) is increasingly used before surgery for colorectal liver metastases (CRC-LM). However, CTx may cause liver injury like steatosis, steatohepatitis, and sinusoidal injury which may be associated with postoperative morbidity. Some recent data have even shown an increased mortality in patients with CTx-associated steatohepatitis. We, therefore, analyzed our recent experience with potential hepatic injury and its association with CTx and morbidity in patients undergoing su...
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Bartholomew’s BioNotes: Take out my liver for chemotherapy please, temporarily that is.
One of the key problems with fighting cancer metastases in the liver is giving enough chemotherapy to fight the cancer without damaging the other parts of the body. Large doses of chemotherapy can def...
[News] Cetuximab for liver metastases from colorectal cancer
Researchers in China have compared outcomes for patients with KRAS wild-type, unresectable, liver-limited metastases from colorectal cancer treated with cetuximab plus chemotherapy or chemotherapy alo...
Liver biopsies can't assess chemotherapy injury
NEW YORK (Reuters Health) - Liver biopsies can't be used to assess chemotherapy associated liver injuries (CALIs), Italian researchers say.
Studies on some 55 U.S. men and women with potentially deadly liver or pancreatic cancers show that specialized MRI scans can tell within a month whether highly toxic chemotherapy is working and killi...
FDA agrees to review Delcath's NDA for chemotherapy device
Delcath Systems said the FDA has accepted its new drug application for the Chemosat liver chemotherapy device and the Alkeran -More-
Faster Testing for Targeted Chemotherapy Effect Against Liver Cancer
Recent studies on men and women with potentially deadly liver or pancreatic cancers showed that new MRI techniques...
Breakthrough Chemo Bath Treatment For Liver Cancer
A treatment that isolates the blood supply to a cancerous liver while the organ receives a "chemo bath" has been used for the first time in the UK. The procedure saturates the liver with high doses...
Is Delcath The Post-Celsion Play On Liver Cancer?
By Brian L. Wilson:Everyone saw the collapse of Celsion Corporation (CLSN) last week, which is something I already covered. As you may know, their drug Thermodox failed Phase III trials for the treatm...
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Chemotherapy, Liver Injury, and Postoperative Complications in Colorectal Liver Metastases.
BACKGROUND: Systemic chemotherapy (CTx) is increasingly used before surgery for colorectal liver metastases (CRC-LM). However, CTx may cause liver injury like steatosis, steatohepatitis, and sinusoida...
BACKGROUND: Systemic chemotherapy may render initially unresectable colorectal cancer liver metastases resectable. Histopathologic examinations of resected nontumoral liver tissue revealed chemotherap...
Steatohepatitis after chemotherapy for colorectal liver metastases (CASH).
Neoadjuvant chemotherapy provides an important treatment option for patients who, as a consequence of colorectal cancer, have developed liver metastases. Regression of metastases prior to surgery may...
Dietary glycine protects from chemotherapy-induced hepatotoxicity.
Hepatotoxic side effects of neoadjuvant chemotherapy for colorectal liver metastases increase perioperative morbidity and mortality. Glycine protects liver from injury in various animal models. Thus,...
Resectable Colorectal Liver Metastases: Optimal Sequencing of Chemotherapy.
BACKGROUND: Hepatic resection is a potentially curative option for patients with colorectal liver metastases who are candidates for surgery. With the increasing availability of highly effective chemot...
