Search Results for "Local Invasion Explained Pancreatic Cancer"
Original Source: Local Invasion of Pancreatic Cancer
Pancreatic cancer often spreads through local invasion into local structures, including fat, blood vessels, nerves, and nearby organs (stomach, duodenum, spleen, bile duct). Local microscopic invasion is associated with recurrence of pancreatic cancer after pancreatic resection, such that even if the original cancer is surgically removed, microscopic areas of cancer often remain. Data on the patterns of local invasion by pancreatic cancer have not been published. In this study,...
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The pancreas secretes a number of important hormones into the digestive tract and the blood stream. Cancers are most commonly exocrine than endocrine (neuroendocrine) tumors. Functional tumors secre...
Epithelial cell adhesion molecule EpCAM CD326
Epithelial cell adhesion molecule (EpCAM; CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian,...
Cervical cancer is a malignant neoplasm of the cervix uteri or cervical area. Symptoms include vaginal bleeding, but may not present until later stages of the cancer. Cervical cancer can be treated...
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In Pancreatic Cancer Model Nerve Growth Factors Elevated
Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancr...
Researcher examines mechanism underlying abdominal pain in pancreatic cancer
Erxi Wu, assistant professor of pharmaceutical sciences, co-wrote the article, "Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells," which was publis...
LIFR protein suppresses local invasion and metastasis of breast cancer cells
A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texa...
Striving to increase survival rates in pancreatic cancer in the UK
Alex Ford, CEO of Pancreatic Cancer UK, shares with us the aims of the charity and highlights how we can raise awareness of pancreatic cancer. Pancreatic cancer is the ninth most common cancer in th...
"Pancreas In A Dish" Will Show How Pancreatic Cancer Forms
A tiny, living 3-D organ model of pancreatic ducts has been created by researchers in Toronto to help them understand pancreatic cancer, which is one of the deadliest yet least understood of all cance...
"Pancreas In A Dish" Helps Scientists Study How Pancreatic Cancer Forms
A tiny, living 3-D organ model of pancreatic ducts has been created by researchers in Toronto to help them understand pancreatic cancer, which is one of the deadliest yet least understood of all cance...
Pancreatic cancer: FDG-PET is not useful in early pancreatic cancer diagnosis
Better tools for early detection and accurate staging of pancreatic cancer are needed. The role of 18F-fluorodeoxyglucose (FDG)-PET in this setting is controversial. The results of a large retrospecti...
3D Culture 96-Well BME Cell Invasion Assay launched by AMSBIO
AMSBIO has announced the launch of the 3D Culture 96-Well BME* Cell Invasion Assay to address the growing need for more complete and physiologically predictive cancer invasion models.
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In our previous study, we found that blockade of SDF-1/CXCR4 signaling inhibits pancreatic cancer cell migration and invasion in vitro. However, the mechanism governing the downstream regulation of SD...
Bone morphogenetic proteins (BMPs) signaling has an emerging role in pancreatic cancer. However, because of the multiple effects of different BMPs, no final conclusions have been made as to the role o...
BACKGROUND:: Recently, cancer stem cells have been reported as a new therapeutic target in pancreatic cancer as well as other cancers, but the specific role of these cells is unknown. METHODS:: The au...
Lymph node (LN) metastasis is one of the most important risk factors for the prognosis of pancreatic cancer. This study aimed to identify novel LN metastasis-associated markers and therapeutic targets...
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation.
We previously identified Hop as over expressed in invasive pancreatic cancer cell lines and malignant tissues of pancreatic cancer patients, suggesting an important role for Hop in the biology of inva...
