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Loratadine syrup reclassified despite RPS concerns

Loratadine syrup has been reclassified from a pharmacy to a general sale list medicine by the Medicines and....

AAPS PharmSciTech: Thermally Triggered Mucoadhesive In Situ Gel of Loratadine: β-Cyclodextrin Complex for Nasal Delivery

Type: Original PaperThe aim of the present study was to increase the solubility of an anti-allergic drug loratadine by making its inclusion complex with β-cyclodextrin and to develop it’s thermally...

CVS Caremark Sponsored Research Finds Consumers Hear Less About Medication Risks When Drugs Switch from Prescription to Over-the-Counter

WOONSOCKET, R.I., Sept. 11, 2012 /PRNewswire/ -- New research sponsored by CVS Caremark and published in this week's issue of the Journal of the American Medical Association (JAMA) identifies dif...

Brain histamine H1 receptor occupancy of loratadine measured by positron emission topography: comparison of H1 receptor occupancy and proportional impairment ratio.

AIMS: We have evaluated the sedative properties of H1-antihistamines by using positron emission tomography (PET) and (11) C-doxepin. The purpose of the present study was to measure histamine H1 recept...

The Effectiveness of Levocetirizine in Comparison with Loratadine in Treatment of Allergic Rhinitis -A Meta-Analysis.

Background: Oral antihistamines are considered the gold standard therapy for allergic rhinitis to date. The goal of this investigation is to make an indirect comparison between loratadine, an oral ant...

Molecularly imprinted nano particles combined with miniaturized homogenous liquid-liquid extraction for the selective extraction of loratadine in plasma and urine samples followed by high performance liquid chromatography-photo diode array detection.

In this work a molecularly imprinted polymer was developed as a selective sorbent for extraction of loratadine (as a model) in complex matrices followed by miniaturized homogeneous liquid-liquid extra...

A new open tubular capillary microextraction and sweeping for the analysis of super low concentration of hydrophobic compounds.

A sample pre-concentration method based on the in-line coupling of in-tube solid-phase microextraction and electrophoretic sweeping was developed for the analysis of hydrophobic compounds. The sample...

Pharmaceutical evaluation and dynamic vapor sorption studies of fast dissolving intraoral films of Loratadine.

The aim of the study was to develop intraoral films (IOFs) of loratadine and to assess the storage conditions by dynamic vapour sorption studies. The excipient selection was guided by drug excipient c...