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LPA1 inhibition induces metastatic dormancy in mouse models of breast cancer
A lysophosphatidic acid receptor 1 (LPAR1) inhibitor, known as Debio-0719, suppresses the development of metastases in mice by inducing cancer cell dormancy, according to a study published August 21 i...
Using 'Acid Reflux' To Kill Cancer Cells
A University of Central Florida chemist has come up with a unique way to kill certain cancer cells - give them acid reflux. Chemistry professor Kevin Belfield used a special salt to make cancer cells...
Genevac Evaporator can Handle Highly Corrosive Chemicals and Acids
Genevac's Acid-Resistant EZ-2 Plus Evaporator uses inert and corrosion-proof materials to enable it to withstand up to 6N Hydrochloric acid, 70% Nitric acid and most acid chlorides including thionyl c...
What Other Neuropathic Pain Drugs Are Missing
By Cris Frangold: When doctors diagnose patients with neuropathic pain, it almost always comes as a shock to patients and family members because it is often difficult to pinpoint and even more difficu...
Omthera asserts Epanova superiority but US filing delayed to next year
Omthera Pharmaceuticals is determined to show that Epanova, its free fatty acid formulation of omega-3 that contains both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), is superior to Ama...
Acid Reflux Treatment | How âHeartburn No Moreâ Helps People Treat Acid Reflux â V-kool
Seattle, Wa (PRWEB) March 29, 2013 Heartburn No More is the newly updated acid reflux treatment method created by Jeff Martin, who promises to help sufferers get rid of acid reflux quickly. The p...
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Lysophosphatidic acid (LPA) stimulates mouse mammary epithelial cell growth.
Lysophosphatidic acid (LPA) is a bioactive phospholipid having diverse effects on various types of tissues. When normal murine mammary gland (NMuMG) cells were cultured in the presence of 0-10 μM LPA...
Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome.
The platelet activator lysophosphatidic acid (LPA) has recently been identified as an ingredient in oxidized LDL and it has been isolated from atherosclerotic plaques. The lysophospholipase D activity...
Cheng R, Shao M-Y, Yang H, Cheng L, Wang F-M, Zhou X-D, Hu T. The effect of lysophosphatidic acid and Rho-associated kinase patterning on adhesion of dental pulp cells. International Endodontic Journa...
Studies show that lysophosphatidic acid (LPA) reprogramming is associated with the development of hepatocellular carcinoma (HCC). This manuscript evaluates the MDR2(-/-) model of HCC as a tool to exam...
This study examined whether propofol and aminophylline affect the mobilization of intracellular calcium in human umbilical vein endothelial cells. Intracellular calcium was measured using laser scanni...