Search Results for "Mass Spectrometry Misoprostol"
Original Source: Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study.
A highly sensitive, selective and evaporation free SPE extraction, ESI-LC-MS/MS method has been developed for estimation of misoprostol free acid in human plasma using misoprostol acid-d(5) as an internal standard (IS). The analyte was separated using isocratic mobile phase on reverse phase column and analyzed by MS/MS in the multiple reaction monitoring mode using the respective [M-H] anions, m/z 367-249 for misoprostol acid and m/z 372-249 for the IS. The total run time was 5.0min and the elution of misop...
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Bruker introduces Toxtyper clinical mass spectrometry solution
At the annual conference of the DGKL, Bruker today announced the European launch of the novel, automated Toxtyper clinical mass spectrometry solution to meet the increasing demands for LC-MS/MS throug...
Mass spectrometry method has promise in diagnosing pancreatic cancer
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Mass Spectrometry Identifies Bacterial and Yeast Isolates
Matrix-assisted laser desorption ionization-time of flight mass spectrometry is an automated molecular platform that can be used to...
Mass Spectrometry: In-depth focus 2013
Corticosteroids and mass spectrometry; latest applications using LC/MS (András Szeitz Faculty of Pharmaceutical Sciences, University of British Columbia)Multi-analyte LC-MS/MS assays for the quantifi...
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New mass spectrometry helps identify bacteria in clinical specimens within minutes
New mass spectrometry technology is helping Le Bonheur Children's physicians analyze microbiology samples quickly - identifying specific bacteria present in a sample within minutes.
Evotec to offer RapidFire Mass Spectrometry analysis capabilities
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An extended mass spectrometry imaging (MSI) service offering from the Mass Spec Imaging Center (MSIC™) has been released. This new service portfolio offers advanced MSI services using LAESI DP-1000...
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A highly sensitive, selective and evaporation free SPE extraction, ESI-LC-MS/MS method has been developed for estimation of misoprostol free acid in human plasma using misoprostol acid-d(5) as an inte...
OBJECTIVES: To evaluate the efficacy and safety of mifepristone and buccal misoprostol versus buccal misoprostol alone in medical abortion of ≤56 days....
OBJECTIVE: To compare the safety, efficacy, and acceptability of 400-mug sublingual misoprostol with that of manual vacuum aspiration (MVA) in 2 Egyptian hospitals. METHODS: Participating women were r...
Effectiveness of misoprostol for office hysteroscopy without anesthesia in infertile patients.
OBJECTIVE: To evaluate and compare the effectiveness of oral and vaginal misoprostol versus placebo to facilitate office hysteroscopy without anesthesia during infertile diagnostic evaluation. DESIGN:...
Randomized trial of oral versus sublingual misoprostol 24 h after mifepristone for medical abortion.
OBJECTIVES: To assess the efficacy, side effects, and acceptability of medical abortion using oral mifepristone (200 mg) followed 24 h later by oral or sublingual misoprostol (400 mug). MATERIALS AND...