Search Results for "Melanin Ulk1"

17:24 EDT 21st September 2017 | BioPortfolio

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Melanin-linked skin conditions: Breakthrough

Spots resulting from too much sun exposure and other effects of dysfunctional melanin production may become a thing of the past. Scientists have solved the structure of one of the three enzymes that g...

Scalable process discovered to produce structural colors inspired by bird feathers

(University of Akron) Researchers made nano-sized balls of melanin aggregate into clusters called supraballs. Melanin appears black in individual nanoparticles. But altering spacing of the nanoparticl...

New breakthrough opens doors to treat melanin-linked skin conditions

(European Synchrotron Radiation Facility) Spots resulting from too much sun exposure and other effects of dysfunctional melanin production may become a thing of the past. Scientists have solved the st...

Scientists have created a ‘sunless tanner’ drug that boosts melanin in skin

Scientists hoping to harness melanin's protective power against skin cancer have found a way to help the skin produce more UV-absorbing pigments.

Researchers look to improve detection of skin cancer lacking pigment melanin

(UNC Lineberger Comprehensive Cancer Center) UNC Lineberger scientists were part of a multi-institution research team that identifed key features linked to amelanotic melanoma, a form of skin cancer t...

Michael Jackson’s Skin

Strange how muchof a man’s life restson melanin, how relations with the sunhave been seeds of societies, markersof what matters. But vitiligodoesn’t know all that. It’s pure obsessionwithout ...

Tans — even from a new drug — aren’t the way to prevent skin cancer

An experimental drug that stimulates skin cells to make melanin, the "tanning" pigment, likely wouldn't do much to prevent skin cancer.

Chemists create the ultimate natural sunscreen

Chemists, materials scientists and nanoengineers have created what may be the ultimate natural sunscreen. They report the development of nanoparticles that mimic the behavior of natural melanosomes, m...

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Ulk1 over-expression in human gastric cancer is correlated with patients' T classification and cancer relapse.

Ulk1 is a key autophagy protein. Here, we tested expression and potential function of Ulk1 in human gastric cancer. Ulk1 mRNA and protein were significantly elevated in multiple fresh human gastric ca...

A small-molecule activator induces ULK1-modulating autophagy-associated cell death in triple negative breast cancer.

ULK1 (unc-51 like autophagy activating kinase 1) is well known to be required to initiate the macroautophagy/autophagy process, and thus activation of ULK1-modulating autophagy/autophagy-associated ce...

ULK1 ubiquitylation is regulated by phosphorylation on its carboxy terminus.

Autophagy is a highly conserved process that acts sequestering cytoplasmic components for their degradation by the lysosomes. It consists of several sequential steps that have to be finely regulated t...

Autophagy up and down by outsmarting the incredible ULK.

Macroautophagy/autophagy initiation is finely regulated by post-translational modifications of key proteins, to comply with the fast kinetics of the cellular response to several stress stimuli. Phosph...

SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways.

Lung cancer is a major public health problem worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer cases. Autophagy has recently sparked great interest, and it is thought to pa...

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