Erectile Dysfunction

Erectile dysfunction (ED or impotence) is the inability to get and maintain an erection that is sufficient for satisfactory sexual intercourse, and affects half of all men between the ages of 40 to...

Alzheimer's Disease

Of all the types of Dementia, Alzheimer's disease is the most common, affecting around 465,000 people in the UK. Neurons in the brain die, becuase  'plaques' and 'tangles'...

Jentadueto® (linagliptin/metformin hydrochloride) tablets recommended for approval

Boehringer Ingelheim and Eli Lilly and Company (NYSE: LLY) announced they have received a positive opinion from the European Medicines Agency's (EMA) medicinal committee recommending approval of Jenta...

Jentadueto® (linagliptin/metformin hydrochloride) tablets recommended for approval in the treatment of adults with type 2 diabetes in Europe

RIDGEFIELD, Conn. and INDIANAPOLIS, May 29, 2012 /- Boehringer Ingelheim and Eli Lilly and Company (NYSE: LLY) today announced they have received a positive opinion from the European Medicines Age...

Pending EC decision: Icandra (previously Vildagliptin/Metformin Hydrochloride Novartis), vildagliptin / metformin, Opinion date: 20-Sep-2012

Human medicines European Public Assessment Report (EPAR): Icandra (previously Vildagliptin/Metformin Hydrochloride Novartis), vildagliptin / metformin, Revision: 7, Authorised

Jentadueto® (linagliptin/metformin…

Jentadueto® (linagliptin/metformin hydrochloride) tablets recommended for approval in the treatment of adults with type 2 diabetes in Europe

Three Type 2 Diabetes Pills From Takeda Approved By FDA

Nesina (alogliptin) tablets, Oseni (alogliptin and pioglitazone) tablets, and Kazano (alogliptin and metformin hydrochloride) tablets, for the treatment of type 2 diabetes, for use along with diet and...

Pending EC decision: Komboglyze, saxagliptin / metformin hydrochloride, Opinion date: 17-Jan-2013

Pending EC decision: Jentadueto , linagliptin / metformin hydrochloride, Opinion date: 24-May-2012

Combination of glibenclamide-metformin HCl for the treatment of type 2 diabetes mellitus.

Introduction: Combination of glibenclamide (glyburide in the U.S.) and metformin hydrochloride simultaneously addresses two different but complimentary mechanisms to improve glycemic control in type 2...

Controlling Release of Metformin HCl through Incorporation into Stomach Specific Floating Alginate Beads.

The aim of present study was to develop stomach specific floating beads of metformin hydrochloride for effective management of type 2 diabetes mellitus. The beads were evaluated for surface morphology...

Determination of metformin hydrochloride using precolumn derivatization with acetaldehyde and capillary electrophoresis coupled with electrochemiluminescence.

A novel method was developed using capillary electrophoresis (CE) coupled with tris(2,2'-bipyridyl)ruthenium(II) electrogenerated chemiluminescence (ECL) for highly sensitive detection of metformin hy...

The Role of Metformin in Metformin-Associated Lactic Acidosis (MALA): Case Series and Formulation of a Model of Pathogenesis.

BACKGROUND: Lactic acidosis is an adverse event associated with metformin usage. Patients with metformin-associated lactic acidosis (MALA), however, often have other conditions contributing to the eve...

Toxicokinetics of metformin-associated lactic acidosis with continuous renal replacement therapy.

A 70-year-old diabetic male patient with a baseline serum creatinine of 1.4 mg/dL presented with nausea and vomiting. He was diagnosed with metformin-associated lactic acidosis and acute kidney injur...