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FDA approves BD Rx's Metoclopramide Injection, USP

The US Food and Drug Administration (FDA) has approved BD Rx's second injectable antiemetic, BD Simplist Metoclopramide Injection, USP.

Metoclopramide, Ondansetron Cut Nausea in Cesarean Delivery

A new study has suggested that adding metoclopramide and ondansetron drugs to a phenylephrine infusion during a cesarean delivery reduces vomiting and nausea. Medscape Medical News

Alabama court: branded manufacturers liable for generics

The Supreme Court of Alabama ruled in Wyeth et al. v. Danny Weeks and Vicki Weeks that a branded drug manufacturer's responsibility for product warnings extends to consumers of generic versions of the...

Olanzapine Overcomes Chemotherapy-Induced Vomiting And Nausea

The antipsychotic out-performed metoclopramide in a Phase III trial of 80 patients with one of four types of cancer who were receiving emetogenic chemotherapy.

New Lawsuit on Reglan Tardive Dyskinesia

According to court documents, on May 29th, 2012, a Minnesota woman, Marilyn Abicht, filed a lawsuit in Minnesota District Court (case no. 0:2012cv01278) alleging that Reglan (metoclopramide) caused he...

Brand-name drugmaker can be sued for harm caused by generic drug

On 4 January 2013 the Alabama Supreme Court ruled that Pfizer can be sued for failing to warn about a drug’s risks by a patient who claimed he was injured by a generic version of its gastric reflux...

Antipsychotic Drug Controls "Breakthrough" Nausea and Vomiting after Chemotherapy

In a phase III clinical trial, the antipsychotic drug olanzapine (Zyprexa) was significantly more effective than metoclopramide (Reglan) in controlling chemotherapy-induced nausea and vomiting (CINV)...

FDA Approves Second Drug in BD Simplist™ Prefilled Injectable Line of Products

FRANKLIN LAKES, N.J., April 23, 2013 /PRNewswire/ -- BD Rx Inc., a wholly-owned subsidiary of leading global medical technology company BD (Becton, Dickinson and Company) (NYSE:BDX), announced to...

Comparison of ondansetron and metoclopramide antiemetic prophylaxis in maxillofacial surgery patients.

PURPOSE: The purpose of this study was to compare the efficacy of ondansetron and metoclopramide, administered for the prophylaxis of vomiting in patients undergoing oral and maxillofacial surgery und...

Metoclopramide as pharmacological tool to assess vasopressinergic co-activation of the hypothalamus-pituitary-adrenal (HPA) axis: A study in healthy volunteers.

The synthetic vasopressin (AVP) analogue desmopressin (dDAVP) has been used as pharmacological function test to quantify vasopressinergic co-activation of the hypothalamus-pituitary-adrenal (HPA) axis...

Effects of metoclopramide on duodenal motility and flow events, glucose absorption, and incretin hormone release, in response to intraduodenal glucose infusion.

The contribution of small intestinal motor activity to nutrient absorption is poorly defined. A reduction in duodenal flow events after hyoscine butylbromide, despite no change in pressure waves, was...

Metoclopramide to augment lactation, does it work? A randomized trial.

Objectives. The objective of this study was to investigate the efficacy of metoclopramide on augmentation of milk production in mothers of premature newborns. Methods. This was a randomized, doubl...

Randomized, double-blinded, placebo-controlled trial of ondansetron plus dexamethasone with or without metoclopramide as antiemetic prophylaxis in patients receiving high-dose cisplatin in medical practice.

PURPOSES: Ondansetron plus dexamethasone are standard antiemetic agents for highly emetogenic chemotherapy. Metoclopramide is a dopamine antagonist, which may enhance efficacy of ondansetron and dexam...