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Search Results for "Microparticles Sepsis"

22:08 EDT 18th May 2013 | BioPortfolio

Original Source: Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response.

Microparticles (MPs) are 0.3 μm to 1.0 μm vesicles generated after cell activation or apoptosis that may play a role in the pathophysiology of sepsis. We sought to elucidate the role of MPs in patients with critical illness and hypothesized that MPs are generated at the site of inflammation and can modulate the immune response.

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Sepsis

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Tumor Necrosis Factor (TNF) and TNF receptor antagonists and agonists used to treat TNF-mediated inflammatory diseases such as rheumatoid arthritis or to treat cancer. TNF blockers are the commerc...

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TNF is a compound that is classified as a cytokine which plays a central role in the cellular mechanisms of apoptosis or cell death. However, there are a number of different kinds of TNF, just under...

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When Breathing Is Impaired, Injecting Oxygen Microparticles Into A Vein Could Save Lives

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood - and fast - to avoid cardiac arrest and brain injury. A team led by rese...

Pharmaceutical Research: Spray-Dried Chitosan Microparticles for Cellular Delivery of an Antigenic Protein: Physico-chemical Properties and Cellular Uptake by Dendritic Cells and Macrophages

Type: Original PaperPurposeSpray-dried chitosan microparticles for cellular delivery of antigen to dendritic cells (DC) and macrophages (Mϕ) were investigated.MethodsChitosan microparticles were prep...

Postpartum Severe Sepsis Rates Are on the Rise

The incidence of severe sepsis and sepsis-related deaths in pregnant and postpartum women increased between 1998 and 2008, although the overall rate of sepsis was stable. Medscape Medical News

Sepsis Partnering 2007-2012

The Sepsis Partnering  2007-2012 provides understanding and access to the sepsis partnering deals and agreements entered into by the worlds leading healthcare companies. The report provides an analys...

Direct injection of oxygen microparticles could deliver oxygen when breathing is impaired

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—right now—to avoid cardiac arrest and brain injury. A team led by res...

Study finds rise in maternal sepsis-related mortality

A new study reports that severity and death rates are increasing in pregnant and postpartum women with sepsis. More than 30 percent of mothers who develop sepsis will experience some type of organ dys...

Injecting life-saving oxygen into a vein: Microparticles could deliver oxygen when breathing is impaired

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—and fast—to avoid cardiac arrest and brain injury. A team led b...

Researchers design microparticles that can deliver oxygen quickly into the bloodstream

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—and fast—to avoid cardiac arrest and brain injury. A team led by res...

Matching PubMed Articles

Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response.

Microparticles (MPs) are 0.3 μm to 1.0 μm vesicles generated after cell activation or apoptosis that may play a role in the pathophysiology of sepsis. We sought to elucidate the role of MPs in patie...

Controlled release behaviour of protein-loaded microparticles prepared via coaxial or emulsion electrospray.

Biodegradable poly (lactic-co-glycolic acid) (PLGA) microparticles are an effective way to achieve sustained drug release. In this study, we investigated a sustained release model of PLGA microparticl...

Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury.

Horizontal information transfer between cells via microparticles is a newly identified communication system. MicroRNAs regulate gene expression and are detected in microparticles. Cantaluppi et al. su...

Enhanced binding of tissue factor-microparticles to collagen-IV and fibronectin leads to increased tissue factor activity in vitro.

The role of tissue factor (TF)-containing microparticles in clot propagation has been established, but the ability of circulating microparticles to initiate coagulation has been disputed. However, TF-...

Preparation and in vivo evaluation of spray dried matrix type controlled-release microparticles of tamsulosin hydrochloride for orally disintegrating tablet.

The objective of this study was to achieve an optimal formulation of spray dried matrix type controlled-release (MTCR) microparticles containing tamsulosin hydrochloride for orally disintegrating tabl...

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