None

When Breathing Is Impaired, Injecting Oxygen Microparticles Into A Vein Could Save Lives

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood - and fast - to avoid cardiac arrest and brain injury. A team led by rese...

Pharmaceutical Research: Spray-Dried Chitosan Microparticles for Cellular Delivery of an Antigenic Protein: Physico-chemical Properties and Cellular Uptake by Dendritic Cells and Macrophages

Type: Original PaperPurposeSpray-dried chitosan microparticles for cellular delivery of antigen to dendritic cells (DC) and macrophages (Mϕ) were investigated.MethodsChitosan microparticles were prep...

Direct injection of oxygen microparticles could deliver oxygen when breathing is impaired

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—right now—to avoid cardiac arrest and brain injury. A team led by res...

Injecting life-saving oxygen into a vein: Microparticles could deliver oxygen when breathing is impaired

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—and fast—to avoid cardiac arrest and brain injury. A team led b...

Researchers design microparticles that can deliver oxygen quickly into the bloodstream

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—and fast—to avoid cardiac arrest and brain injury. A team led by res...

Pharmaceutical Research: Critical Solvent Properties Affecting the Particle Formation Process and Characteristics of Celecoxib-Loaded PLGA Microparticles via Spray-Drying

Type: Original PaperPurposeIt is imperative to understand the particle formation mechanisms when designing advanced nano/microparticulate drug delivery systems. We investigated how the solvent power a...

Oncology Clinical Trials Congress And Oncology Clinical Trials In Emerging Regions, 13-14 May 2013, Prague, Czech Republic

Adaptive Clinical Trial: Translation in Action - How statistics can effectively couple clinical trials & personalised medicine in Oncology. Clinical trials run by pharmaceutical and biotech companies...

[Comment] Regulating clinical trials in Europe

Many medical researchers seem to agree that the European legislation on clinical trials needs to change. Between 2007 and 2011, the number of clinical trials started in Europe fell by 25%. Much critic...

Controlled release behaviour of protein-loaded microparticles prepared via coaxial or emulsion electrospray.

Biodegradable poly (lactic-co-glycolic acid) (PLGA) microparticles are an effective way to achieve sustained drug release. In this study, we investigated a sustained release model of PLGA microparticl...

Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury.

Horizontal information transfer between cells via microparticles is a newly identified communication system. MicroRNAs regulate gene expression and are detected in microparticles. Cantaluppi et al. su...

Enhanced binding of tissue factor-microparticles to collagen-IV and fibronectin leads to increased tissue factor activity in vitro.

The role of tissue factor (TF)-containing microparticles in clot propagation has been established, but the ability of circulating microparticles to initiate coagulation has been disputed. However, TF-...

Preparation and in vivo evaluation of spray dried matrix type controlled-release microparticles of tamsulosin hydrochloride for orally disintegrating tablet.

The objective of this study was to achieve an optimal formulation of spray dried matrix type controlled-release (MTCR) microparticles containing tamsulosin hydrochloride for orally disintegrating tabl...

Inhalable Microparticles as Carriers for Pulmonary Delivery of Thymopentin-Loaded Solid Lipid Nanoparticles.

PURPOSE: Microparticles containing solid lipid nanoparticles (SLNs) are receiving increased attention as carriers for the lung delivery of the SLNs. Thus, we aim to prepare the hybrid microparticles a...