Parkinson's Disease

Parkinson's is a progressive neurological condition, affecting one person in every 500, 95% of which are over 40. It is caused by degeneration of more than 70% of the substantia nigra, which dep...

Atrial Fibrillation and WolffParkinsonWhite Syndrome WPW

Metabotropic Glutamate Receptor 4 (mGluR4)

Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor famil...

Selective monoamine oxidase type B MAOB inhibitors

The clinical benefit of monoamine oxidase type B (MAO-B) inhibitors is thought to arise from an ability of these medications to enhance the level of dopamine by decreasing the catabolism. Additional...

Neurotrophic Growth Factors NGF BDNF CNTF

Early clinical trials with classical neurotrophic growth factor proteins such as NGF, BDNF, CNTF have failed for various reasons including safety, efficacy and convenience of administration as well as...

Cebix raises $30.9 million for treating diabetes related microvascular problems

Cebix is moving ahead in its development of C-peptide replacement therapy for treating diabetes-related microvascular problems.Encouraging results from an early stage trial, reported earlier this mont...

Early Diagnosis Of Parkinson's May Be Possible With Discovery Of New Antibody

Around 15,000 to 16,000 Austrian's suffer from Parkinson's disease, a degenerative condition of the brain, which becomes more prevalent with age. The frequency of Parkinson's disease will become more...

Far-reaching, microvascular damage found in uninjured side of brain after stroke

An animal-model study finds far-reaching microvascular damage in the uninjured side of the brain after a stroke. The findings suggest repair of the protective blood-brain barrier may help prevent this...

Researchers find far-reaching, microvascular damage in uninjured side of brain after stroke

While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida...

Parkinson’s UK welcomes introduction of Best Practice Tariff for Parkinson’s

 Parkinson’s UK today welcomes the introduction of the Department of Health’s new Best Practice Tariff (BPT) for Parkinson’s. It is hoped that the tariff – which will encourage first-clas...

Depression a Key Factor in Health of Parkinson's Patients: Study

WEDNESDAY, Nov. 28 (HealthDay News) -- Depression is the most important determinant of the health status of people with Parkinson's disease, according to early findings from a large study of Parkins...

'Clean-Up' Snafu That Kills Brain Cells In Parkinson's Disease Identified

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which publ...

Anonymous survey launched for Parkinson’s patients to collect data for research to help determine the cause of Parkinson's disease.

Yelm, Wa (PRWEB) February 20, 2013 An anonymous survey has been launched by the Parkinson’s Database Coalition for those afflicted with Parkinson’s disease. The survey is for Parkins...

Rapid automatic assessment of microvascular density in sidestream dark field images.

The purpose of this study was to develop a rapid and fully automatic method for the assessment of microvascular density and perfusion in sidestream dark field (SDF) images. We modified algorithms prev...

Parkinson disease: Improving quality of care in Parkinson disease.

Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties.

Brain microvascular disorders, including cerebral microscopic hemorrhage, have high prevalence but few treatment options. To develop new strategies for these disorders, we analyzed the effects of seve...

Renal Microvascular Disease Predicts Renal Function in Diabetes.

Abstract Renal microvascular disease reflected directly by peritubular capillary flow reduction and indirectly by renal function impairment has been documented in early diabetic nephropathy (DN) ass...

Evaluation of microvascular density in Barrett's associated neoplasia.

Angiogenesis has an important role in the carcinogenesis of esophageal adenocarcinoma, however, the diagnostic and prognostic utility of microvascular density counts have not been clinically establish...