Gastrointestinal Effects

RPL554

Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...

Adverse drug effects

Resistance to effects of vitamin D

Management of Adverse Effects

IV antipsychotic a good adjunct to midazolam in acutely agitated ED patients

NEW YORK (Reuters Health) - For acutely agitated patients in the emergency department (ED), supplementing midazolam with an IV bolus of droperidol or olanzapine provided more rapid and adequate se...

IV Combos Work for Agitation in the ED (CME/CE)

(MedPage Today) -- For patients with acute agitation in the emergency department, adding either droperidol or olanzapine to midazolam reduces the time to sedation compared with midazolam alone, a rand...

Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At α1 Subunit-Containing GABAA Receptor Subtypes in Midazolam- But Not Cocaine-Experienced Rhesus Monkeys

Maple Syrup T-Shirt Giveaway Mohawk Valley Trading Company

New York, NY (PRWEB) April 01, 2013 The Mohawk Valley Trading Company is giving away one Maple Syrup T-Shirt with each order of Maple Syrup from 4/02/13 thru 4/09/13 with the promo code 40913. T...

Steviva Brands Unveils Stevia-Based Syrup Blend Designed to Replace High Fructose Corn Syrup in Beverages

Portland, Oregon (PRWEB) January 26, 2013 Steviva Brands, Inc., one of the world’s leading manufacturers and distributors of stevia-based sweeteners and other bulk-ingredient sweeteners, has i...

Maple syrup, moose, and the local impacts of climate change

(Cary Institute of Ecosystem Studies) In the northern hardwood forest, climate change is poised to reduce the viability of the maple syrup industry, spread wildlife diseases and tree pests, and change...

Mohawk Valley Trading Company Maple Syrup T-Shirt Giveaway

(PRWEB) April 06, 2013 The Mohawk Valley Trading Company is giving away one Maple Syrup T-Shirt with each order of their 32 oz. glass bottle of maple syrup from 4/07/13 thru 4/14/13 with the â€...

FDA Nixes Name Change for Corn Syrup

(MedPage Today) -- The FDA was not so sweet regarding a petition from the Corn Refiners Association to replace the term "high fructose corn syrup" with "corn sugar."

Stability of midazolam hydrochloride injection 1-mg/mL solutions in polyvinyl chloride and polyolefin bags.

Purpose The stability of midazolam hydrochloride injection 1-mg/mL solutions in polyvinyl chloride (PVC) and polyolefin bags under varying conditions was evaluated. Methods Triplicate solutions of mid...

Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect-Physiologic and Genomic Investigations with Rats.

Rats fed a 20%-maple syrup diet (maple syrup group) for 11 d showed significantly lower values of the hepatic function markers than those fed a 20%-sugar mix syrup diet (control). The reason was sugge...

A pharmacodynamic-pharmacokinetic (PD-PK) study on the effects of Danshen (Salvia miltiorrhiza) on midazolam, a model CYP3A probe substrate, in the rat.

This study investigated the effect of Danshen on the pharmacodynamic-pharmacokinetic (PD-PK) effects of midazolam, a model CYP3A probe substrate. The effects of acute and 3-day Danshen treatment on th...

Combined strategies for enhancing the transdermal absorption of midazolam through human skin.

Objectives Midazolam administration by intravenous or intramuscular injection produces pain and stress. For this reason, alternative methods of administration have been proposed. The transdermal admin...

Intranasal Midazolam: Pharmacokinetics and Pharmacodynamics Assessed by Quantitative EEG in Healthy Volunteers.

The pharmacokinetics and pharmacodynamics of a highly concentrated cyclodextrin-based intranasal (i.n.) midazolam formulation containing the absorption-enhancer chitosan were studied in 12 healthy vol...