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A tumor or tumour is the name for a neoplasm or a solid lesion formed by an abnormal growth of cells (termed neoplastic) which looks like a swelling. Tumor is not synonymous with cancer. A tumor can...
A contract research organization, also called a clinical research organization, (CRO) is a service organization that provides support to the pharmaceutical and biotechnology industries in the form o...
Early clinical trials with classical neurotrophic growth factor proteins such as NGF, BDNF, CNTF have failed for various reasons including safety, efficacy and convenience of administration as well as...
Multimodal analgesia regimens may help improve pain management after spine surgery while reducing the need for opioids. Journal of the American Academy of Orthopaedic Surgeons
When included in multimodal analgesic regimens, is gabapentin associated with respiratory depression during post-anesthesia recovery after major laparoscopic procedures? Anesthesia & Analgesia
This study suggests that local infiltration analgesia during surgery may have a beneficial impact on postoperative inflammation in patients undergoing total hip arthroplasty. BMC Anesthesiology
Which patients may benefit from the use of IV patient-controlled analgesia in the hospital setting? This article presents a framework for the selection of patients, analgesic agents, and dosing. U.S...
Do mechanically ventilated trauma patients with a positive urine drug screen for cocaine and/or amphetamines require higher doses of analgesic and sedative medications? Anesthesia & Analgesia
Imaging and endoscopy remains key to the diagnosis of gastrointestinal malignancies, especially for early disease detection. Here, the authors describe multimodal imaging techniques and how they can b...
(Elsevier) Elsevier, the information analytics company specializing in science and health, today announced that it will be the new publisher of Veterinary Anaesthesia and Analgesia beginning in the sp...
Investigators found an 8-week multimodal treatment program for patients with knee osteoarthritis that included a cycle of intra-articular injections of sodium hyaluronate administered weekly was cost-...
Ambulatory surgery has grown in popularity in recent decades due to the advancement in both surgical and anesthetic techniques resulting in quicker recovery times, fewer complications, higher patient ...
Cesarean delivery is a commonly performed procedure worldwide. Despite improvements in balanced multimodal analgesia, there remains a proportion of women for whom postoperative pain relief and patient...
: Multimodal analgesia, which combines analgesic drugs from different classes and employs analgesic techniques that target different mechanisms of pain, is recommended in the treatment of acute postop...
Gabapentinoids are widely used in perioperative multimodal analgesic regimens. The primary aim of this study was to determine whether gabapentin was associated with respiratory depression during phase...
Morphine-6-O-sulfate (M6S) is a mixed μ/δ-opioid receptor (OR) agonist and potential alternative to morphine for treatment of chronic multimodal pain.