Search Results for "Myelin Damage"
Original Source: Myelin damage of hippocampus and cerebral cortex in rat pentylenetetrazol model.
Epilepsy is a chronic neurological disorder characterized by spontaneous recurrent seizures, which also occur in demyelinating diseases of the central nervous system (CNS) with a higher prevalence. Meanwhile, demyelination occurrings have been occasionally observed in CNS of epilepsy patients, indicating an association between demyelination and epileptic seizures by an unknown mechanism. However, no confirmative experimental evidence has yet been given. Thus, by using a rat pentylenetetrazol model, electroe...
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Multiple sclerosis (MS) is the most common disabling neurological condition affecting 100,000 young adults in the UK. The condition results from autoimmune damage to myelin, causing interference i...
Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in term...
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Repair Of Multiple Sclerosis Brain Damage May Be Possible
In what they describe to the press as a "life-changer" for millions of people with the disease, researchers in the US report this week a study where they discovered blocking an enzyme in the brain ma...
MRF announces achievement of myelin repair Phase 1 trial for MS
The Myelin Repair Foundation (MRF) today announced the achievement of a myelin repair Phase 1 clinical trial for multiple sclerosis earlier than the foundation's goal set for 2014. By establishing its...
Social Isolation Reduces Myelin Production
A new US study finds that depriving adult mice of social contact reduces production of myelin, the protein sheath that surrounds the fibers or axons that convey electrical signals between nerve cells...
Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins
Scientists identify inhibitor of myelin formation in central nervous system
Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming...
The Myelin Repair Foundation (MRF) today announced the support of the Ballenger Trust to accelerate the development of myelin repair therapeutics for multiple sclerosis (MS...
Inhibitor Of Myelin Formation Identified In The Central Nervous System
Scientists at the Mainz University Medical Center have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduc...
Patients' skin could repair MS damage
The MS Society has welcomed research which suggests that it may be possible to use a patient’s own skin to repair the damage caused by multiple sclerosis. Nerves struggle to communicate in MS a...
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Myelin is a biologically active mutilamellar that is formed by oligodendrocytes (OLs) in the central nervous system (CNS) and ensheathes axons (Ishii et al., Proc Natl Acad Sci USA 106:14605-14610, 20...
Myelin damage of hippocampus and cerebral cortex in rat pentylenetetrazol model.
Epilepsy is a chronic neurological disorder characterized by spontaneous recurrent seizures, which also occur in demyelinating diseases of the central nervous system (CNS) with a higher prevalence. Me...
Performing 2-DE of lipid-rich multilamellar membranes like myelin is a cumbersome task. However, for understanding its molecular organization and changes during diseases, identification of proteins of...
Anti neural antibodies are known to play a role in the immunopathogenesis of nerve damage in leprosy and HIV/AIDS. Myelin Protein zero (P0) and ceramide are two nerve components which maintain the int...
Signaling mechanisms regulating myelination in the central nervous system.
The precise and coordinated production of myelin is essential for proper development and function of the nervous system. Diseases that disrupt myelin, including multiple sclerosis, cause significant f...
