Neuromyelitis Optica

An early British case of neuromyelitis optica (1850)

The term neuromyelitis optica (Devic’s syndrome) refers to the co-occurrence of acute myelitis and optic neuritis. Regarded for many decades as a clinical variant of multiple sclerosis, neuromyeliti...

Researchers stop neuromyelitis optica attacks with new therapy

Researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating central nervous system disor...

New Therapy Halts Neuromyelitis Optica Attacks

Mayo Clinic researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating central nervous...

[Articles] Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study

Eculizumab seems to be well tolerated, significantly reduce attack frequency, and stabilise or improve neurological disability measures in patients with aggressive neuromyelitis optica spectrum disord...

A Possible Marker for Diagnosing Neuromyelitis Optica

A common, painful symptom could be useful in the diagnosing of neuromyelitis optica. Medscape Neurology

[Comment] Hope for a rare disease: eculizumab in neuromyelitis optica

Neuromyelitis optica (also known as Devic's syndrome) is a rare severe inflammatory CNS disorder that clinically manifests with attacks of optic neuritis and myelitis. For a long time, the disorder wa...

Mayo Clinic researchers stop neuromyelitis optica attacks with new therapy

(Mayo Clinic) Mayo Clinic researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating ce...

Mayo researchers discover new therapy for patients with neuromyelitis optica

Mayo Clinic researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating central nervous...

IFN{beta}-1b may severely exacerbate Japanese opticspinal MS in neuromyelitis optica spectrum: Japanese optic-spinal MS: Is it MS or neuromyelitis optica and does the answer dictate treatment?

Diagnosis and treatment of neuromyelitis optica : Consensus recommendations of the Neuromyelitis Optica Study Group.

Intractable vomiting as the initial presentation of neuromyelitis optica.

We report 12 aquaporin-4 antibody-positive patients (12% of seropositive Mayo Clinic patients identified since 2005) whose initial presenting symptom of neuromyelitis optica was intractable vomiting....

A population-based study of neuromyelitis optica in Caucasians.

Epidemiologic studies have suggested different prevalence of neuromyelitis optica (NMO) in different ethnic groups. However, data on the incidence and prevalence of NMO in Caucasians are scarce.

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.

Devic's neuromyelitis optica is an inflammatory demyelinating disorder normally restricted to the optic nerves and spinal cord. Since the identification of a specific autoantibody directed against aqu...