ATX-MS-1467 for patients with multiple sclerosis (MS)

ATX-MS-1467 is a novel treatment that was developed with the aim of working with the immune system to treat the underlying cause of disease rather than just treating the symptoms or suppressing the...

Clinical Approvals - news, views, reports and blogs

Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and eff...

Xofigo (radium-223 dichloride)

New treatment for castration-resistant prostate cancer (CRPC) patients with bone metastases. Xofigo shown in a pivotal phase III trial to significantly improve overall survival. Xofigo® with...

Vitamin E Toxicity

Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...

Contract Research Organization news

A contract research organization, also called a clinical research organization, (CRO) is a service organization that provides support to the pharmaceutical and biotechnology industries in the form o...

Update on the Tuscia Trial

Last week, we heard about a trial of genetically engineered trees and vines at the University of Tuscia, Italy that is being threatened with being cut down. There has been some information in the news...

Featured Clinical Trial: Targeting Invasive Glioma Cells

The name of the trial is Phase I Trial of AZD7451, a Tropomyosin-Receptor Kinase (TRK) Inhibitor, for Adults with Recurrent Gliomas (NCI-12-C-0005).

Pfizer vows to learn from virtual trial failure

Several months after Pfizer failed to recruit patients to its first ever virtual trial, the firm said it was looking to learn from the setback. The pilot REMOTE trial was looking to recruit 600 patien...

[News] Data used to justify Indian HPV vaccination trial questioned

A trial of human papillomavirus (HPV) vaccines in India, halted by the Indian Government in 2010, ran into fresh controversy with the publication of a study suggesting that the trial should not have b...

Topol: Get Rid of the Randomized Trial; Here's a Better Way

Dr. Eric Topol wants to throw out the 'contrived' randomized, placebo-controlled trial and launch the clinical trial of the future. Here's how he'd do it. Medscape

Implementing adaptive trial design to improve efficacy and accurate results collection

In adaptive trials, data gathered as the trial progresses are used to change some aspect of the trial mistream. These trials have increased over the [...]

Major Milestone Achieved in CytRx’s Phase 2b Global Clinical Trial with Tamibarotene as a ...

Independent Data Safety Monitoring Board recommends continuation of Phase 2b trial Trial data expected in 2013

SPIRIT 2013 clinical trial protocol guidelines issued

(HealthDay)—A panel of experts, including trial investigators, trial coordinators, and representatives from ethics and regulatory agencies, has developed the Standard Protocol Items: Recommendations...

Do messages of scarcity increase trial recruitment?

INTRODUCTION: Psychological theory suggests that participants may be more likely to volunteer to join a clinical trial if they perceive places in the trial are a scarce commodity. MATERIAL AND METHODS...

Teaching Evidence-Based Practice Using a Mock Trial.

The mock trial, which is an educational tool used in many different professions, is a scripted form of debate that teaches the critical thinking process. Using the mock trial approach, two nurse educa...

Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe.

ABSTRACT: BACKGROUND: We examined the use of male condoms and the diaphragm following completion of a clinical trial of the diaphragm's HIV prevention effectiveness. In the trial, called Methods for I...

Trial watch: Apixaban beats warfarin in stroke trial.

Trial watch: Sepsis study failure highlights need for trial design rethink.