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Search Results for "Nortriptyline Lc Ms Ms"

01:53 EDT 26th May 2013 | BioPortfolio

Original Source: Rapid and sensitive LC-MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma.

Felbamate (2-phenyl-1,3-propanediol dicarbamate) is a second generation antiepileptic drug used to treat seizures refractory to other antiepileptic drugs. With approximately 3500 new patients exposed annually, several important pharmacologic interaction questions remain unanswered necessitating the need for rapid and accurate methods of felbamate analysis in biological matrices. To this end, a rapid liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the measurement of felbama...

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Nortriptyline Minimal Benefit in Gastroparesis

The tricyclic antidepressant improved some symptoms of gastroparesis, but its benefits were limited. Almost 30% of the nortriptyline arm discontinued study due to side effects. Medscape Medical News

Nortriptyline no help for smoking cessation in prison study

NEW YORK (Reuters Health) - Adding the antidepressant nortriptyline to conventional smoking cessation therapy didn't improve long-term success among male prisoners, Australian researchers have fou...

Mood drug no help for smoking cessation in prison study

NEW YORK (Reuters Health) - The addition of the antidepressant nortriptyline to conventional smoking cessation therapy didn't improve the chances of longterm success among male prisoners, Australian r...

New Study With CHANTIX®/CHAMPIX® (varenicline) Tablets Suggests Favorable Benefit-Risk Profile In Adult Smokers With Major Depressive Disorder

Pfizer Inc. (NYSE: PFE) announced today the completion of a double-blind, placebo-controlled, randomized clinical trial designed to assess the efficacy and safety of CHANTIX®/CHA...

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Nortriptyline for treating enuresis in ADHD-a randomized double-blind controlled clinical trial.

BACKGROUND: Treating enuresis in children with attention deficit hyperactivity disorder (ADHD) has not been previously reported. This study aims to investigate the efficacy, tolerability, and adverse...

Translating the smoking cessation properties of the antidepressant nortriptyline using reinforcing, discriminative and aversive stimulus effects of nicotine in rats.

RATIONALE: The antidepressant nortriptyline is a second-line pharmacotherapy for smoking cessation. Given that there is limited preclinical data available on the effects of nortriptyline on responses...

Change in cognitive functioning in depressed older adults following treatment with sertraline or nortriptyline.

OBJECTIVE: The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults. METHODS: We used pre-post neuropsychological dat...

Changes in body weight during pharmacological treatment of depression.

The risk of weight gain is an important determinant of the acceptability and tolerability of antidepressant medication. To compare changes in body weight during treatment with different antidepressant...

Topiramate plus nortriptyline in the preventive treatment of migraine: a controlled study for nonresponders.

A sizeable proportion of migraineurs in need of preventive therapy do not significantly benefit from monotherapy. The objective of the study is to conduct a randomized controlled trial testing whether...

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