Getting a grip on O-acetyl-ADP-ribose - Nature Structural ...
Two papers now implicate O-acetyl-ADP-ribose, the metabolite produced by this reaction, as a small-molecule effector that binds to heterochromatic proteins.
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http://www.nature.com/nsmb/journal/v12/n7/full/nsmb0705-560....
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BioPortfolio - O-Acetyl-ADP-Ribose
BioPortfolio Ltd. offers e-mail and postal lists for O-Acetyl-ADP-Ribose scientists - we have details of around 3 individuals working on O-Acetyl-ADP-
Ribose ...
http://www.bioportfolio.com/indepth/O-Acetyl-ADP-Ribose.html...
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The 39-kDa poly(ADP-ribose) glycohydrolase ARH3 hydrolyzes O ...
We hypothesized that, if O-acetyl-ADP-ribose were an important signaling molecule, ... The rate of O-acetyl-ADP-ribose hydrolysis by recombinant ARH3 was
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http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=16...
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BioPortfolio - O-Acetyl-ADP-Ribose - InDepth
Bypassing Sir2 and O-acetyl-ADP-ribose in transcriptional silencing. ... Synthesis and biochemical evaluation of O-acetyl-ADP-ribose and N-acetyl analogs
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http://www.bioportfolio.com/indepth/O-Acetyl-ADP-Ribose.pdf...
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Bypassing Sir2 and O-acetyl-ADP-ribose in transcri...[Mol Cell ...
A by-product of the Sir2 reaction, O-acetyl-ADP-ribose (OAADPr), is thought to ... Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, ...
http://www.ncbi.nlm.nih.gov/pubmed/18775325...
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Structural identification of 2'- and 3'-O-acetyl-A...[J Biol Chem ...
Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein ...
http://view.ncbi.nlm.nih.gov/pubmed/11893743...
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Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as ...
Sir2 enzymes have been shown to couple substrate deacetylation and beta-NAD(+) cleavage to the formation of O-acetyl-ADP-ribose, a newly described ...
http://www.ncbi.nlm.nih.gov/pubmed/11893743...
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Conserved enzymatic production and biological effe...[J Biol Chem ...
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. ...
http://view.ncbi.nlm.nih.gov/pubmed/11812793...
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Analysis of O-acetyl-ADP-ribose as a target for Nu...[J Biol Chem ...
Recent evidence has indicated that these proteins produce a novel metabolite O- acetyl-ADP-ribose (OAADPr) during deacetylation. ...
http://www.ncbi.nlm.nih.gov/pubmed/12370179...
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Structural basis for nicotinamide cleavage and ADP-ribose transfer ...
These enzymes bind NAD+ and acetyllysine within protein targets and generate lysine, 2′-O-acetyl-ADP-ribose, and nicotinamide products. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=42...
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