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Search Results for "Oral Bioavailability Of Triazolam"

09:02 EDT 18th May 2013 | BioPortfolio

Original Source: Triazolam Trial In Healthy Subjects To Compare Bioavailability Between Formulations Of Triazolam To Determine Their Bioequivalence In Terms Of Rate And Magnitude Of Absorption

The purpose of this study is to compare the bioavailability of two oral formulations of Triazolam in healthy volunteers, in order to determine that they are bioequivalent.

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AAPS PharmSciTech: Development of Amphotericin B-Loaded Cubosomes Through the SolEmuls Technology for Enhancing the Oral Bioavailability

Type: Original PaperThe oral administration of amphotericin B (AmB) has the major drawback of poor bioavailability. The aim of this work was to evaluate the potential of AmB-loaded cubosomes as an ora...

The AAPS Journal: Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice

Type: Original PaperLenalidomide is a synthetic derivative of thalidomide exhibiting multiple immunomodulatory activities beneficial in the treatment of several hematological malignancies. Murine phar...

AAPS PharmSciTech: Improving Oral Bioavailability and Pharmacokinetics of Liposomal Metformin by Glycerolphosphate–Chitosan Microcomplexation

Type: Original PaperThe purpose of this study was to develop a new delivery system capable of improving bioavailability and controlling release of hydrophilic drugs. Metformin-loaded liposomes were pr...

AAPS PharmSciTech: Formulation and In Vivo Evaluation of Orally Disintegrating Tablets of Clozapine/Hydroxypropyl-β-cyclodextrin Inclusion Complexes

Type: Original PaperThe aim of this study was to improve the solubility and oral bioavailability of clozapine (CLZ), a poorly water-soluble drug subjected to substantial first-pass metabolism, employi...

Agere Bioavailability Technology Analysis Shows Promise to Expand Pharmaceutical Industry

Agere Pharmaceuticals, Inc., a leading oral bioavailability contract research and manufacturing organization (CRO/CMO), will deliver a webinar presentation followed by an interact...

Unigene and Tarix report highly increased oral bioavailability of "Peptelligence-engineered" TXA127

USA-based Unigene Laboratories Laboratories (OTCBB: UGNE) and Tarix Pharmaceuticals yesterday announced the successful completion of a feasibility study of an oral formulation of TXA127, Tarix' lead p...

Excipients Top List of Hot Topics at The Bioavailability Challenge

Formulators still think of excipients first when faced with drug bioavailability difficulties judging by trends that emerged at our online event.

Dow Signs Up Cambrex for Bioavailability Partnership

Dow has contracted Cambrex to make its solubility enhancing polymer HPMCAS, adding manufacturing clout to its bioavailability-focused collaboration with Bend Research.

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Effects of dosing interval on the pharmacokinetic and pharmacodynamic interactions between the oral adsorbent AST-120 and triazolam in humans.

OBJECTIVE: The objective of this study was to evaluate the pharmacokinetic and pharmacodynamic interactions between the oral adsorbent AST-120 and triazolam. METHODS: In this randomized, cross-over st...

Physiological doses of progesterone potentiate the effects of triazolam in healthy, premenopausal women.

RATIONALE: Gender plays a critical role in the effects of drugs and drug abuse liability. Biological factors, including ovarian hormones, may contribute to gender differences in drug abuse. Preclinica...

Cognitive effects of intramuscular ketamine and oral triazolam in healthy volunteers.

RATIONALE: Several studies have documented impairments in memory processes as a result of ketamine administration; however, few studies have compared the profile of cognitive effects of ketamine to ot...

Imprinted functionalized silica sol-gel for solid-phase extraction of triazolamin.

A triazolam-imprinted silica microsphere was prepared by combining a surface molecular-imprinting technique with the sol-gel process. The results illustrate that the triazolam-imprinted silica microsp...

Bioavailability of oral methylnaltrexone increases with a phosphatidylcholine-based formulation.

Abstract Objective: Methylnaltrexone (MNTX), a peripherally restricted opioid antagonist with mu-opioid receptor selectivity, can reduce opioid activity in the gastrointestinal tract while sparing the...

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