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In Waldenstrm macroglobulinemia, fludarabine yields better survival than chlorambucil

NEW YORK (Reuters Health) - Fludarabine improves survival compared with chlorambucil in patients with Waldenstrm macroglobulinemia (WM) and related disorders, according to the multicenter WM1 stud...

Fludarabine can't replace cyclophosphamide with busulfan myeloablative conditioning

NEW YORK (Reuters Health) - In patients with leukemia and myelodysplastic syndrome who need myeloablative conditioning before allogeneic hematopoietic cell transplantation (HCT), the less toxic...

Toxic erythema of chemotherapy following i.v. BU plus fludarabine for allogeneic PBSC transplant

BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells

Fludarabine-induced severe necrotizing leukoencephalopathy in pediatric hematopoietic cell transplantation

Reduced-intensity conditioning with fludarabine and thiotepa for second allogeneic transplantation of relapsed patients with AML

Impact of lymphocyte and monocyte recovery on the outcomes of allogeneic hematopoietic SCT with fludarabine and melphalan conditioning

Fludarabine and cyclophosphamide in combination with alemtuzumab in patients with primary high-risk, relapsed or refractory chronic lymphocytic leukemia

Fludarabine combined with radiotherapy in patients with locally advanced NSCLC lung carcinoma: a phase I study.

BACKGROUND AND PURPOSE: Fludarabine is an adenine nucleoside analogue that has significant activity in hematological malignancies and has shown promising activity in combination with radiation in prec...

The value of rituximab for the treatment of fludarabine-refractory chronic lymphocytic leukemia: A systematic review and qualitative analysis of the literature.

Abstract The increase of fludarabine-resistant chronic lymphocytic leukemia (CLL) presents a new treatment challenge. The aim of this review is to evaluate the efficacy and safety of rituximab for p...

Non-gastric marginal zone B cell lymphoma: clinicopathologic features and treatment results.

The optimal treatment strategy and outcome of non-gastric marginal zone lymphoma (MZL) remains undefined. The role of rituximab and fludarabine in MZL has not been critically appraised and compared wi...

The Impact of Initial Fludarabine Therapy on Transformation to Richter's Syndrome or Prolymphocytic Leukemia in Patients with Chronic Lymphocytic Leukemia: Analysis of an Intergroup Trial (CALGB 9011).

Abstract The impact of initial fludarabine therapy on transformation to Richter's syndrome (RS) or prolymphocytic leukemia (PLL) in chronic lymphocytic leukemia (CLL) patients is uncertain. We studied...

Bendamustine compared to fludarabine as second-line treatment in chronic lymphocytic leukemia.

Bendamustine demonstrated clinical activity in pre-treated hematological malignancies due to its unique mechanism of action distinct from standard alkylating agents. This study assessed its efficacy i...