Wuerzburg bleb classification score WBCS

Tumor Antigens

Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates f...

Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a chronic, life-threatening disorder characterized by abnormally high blood pressure in the arteries between the heart and lungs of an affected individual. T...

Biopharmaceuticals - news, views, blogs and reports

Biopharmaceuticals are medical drugs (see pharmacology) produced using biotechnology. They include proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) and living...

FDA approves OTC Oxytrol for Women for overactive bladder

The FDA has approved Merck’s Oxytrol for Women, the first over-the-counter treatment for overactive bladder in women ages 18 years and older. Oxytrol will remain available for men with overactive bl...

Merck’s Oxytrol Could Go From Rx Also-Ran To OTC Star – Analysts

Watson’s Oxytrol currently has just a 1% share of the overactive bladder drug market, but Kline and Kalorama analysts see sizable potential should it switch OTC.

Merck Seeks Oxytrol Switch For Women As First Overactive Bladder OTC

Merck will present to FDA’s Nonprescription Drugs Advisory Committee Nov. 9 in support of switching Watson’s Oxytrol as a female-specific OTC.

FDA approves OXYTROL® FOR WOMEN

Merck announced that the U.S. FDA has approved OXYTROL FOR WOMEN, the first and only over-the-counter treatment for overactive bladder in women...

Merck’s Oxytrol Could Be OTC Trailblazer For Chronic Conditions

Merck’s Oxytrol for Women has the opportunity to “create the market” for OTC overactive bladder drugs, as well as encourage other switches for chronic, progressive conditions, marketing consulta...

NDAC Puts Hitch In Oxytrol Switch With Negative Self-Selection Vote

In a 6-5 vote, FDA’s Nonprescription Drugs Advisory Committee said Merck failed to show that consumers can appropriately self-select to use Oxytrol for Women in an OTC setting. The company expects t...

Oxytrol For Women Gets OTC Green Light As Rare First-In-Class Switch

FDA approved Merck’s overactive bladder drug Oxytrol for Women for OTC use, despite concerns raised by the Nonprescription Drug Advisory Committee in November. The company plans a launch in the fall...

Merck receives FDA approval for Oxytrol to treat overactive bladder in women

The U.S. Food and Drug Administration today approved Oxytrol for Women, the first over-the-counter treatment for overactive bladder in women ages 18 years and older.

Classification models for neocryptolepine derivatives as inhibitors of the β-haematin formation.

This paper describes the construction of a QSAR model to relate the structures of various derivatives of neocryptolepine to their anti-malarial activities. QSAR classification models were build using...

Is overall similarity classification less effortful than single-dimension classification?

It is sometimes argued that the implementation of an overall similarity classification is less effortful than the implementation of a single-dimension classification. In the current article, we argue...

Classification of Organic Solvents Revisited by Using the COSMO-RS Approach.

A new approach for the classification of solvents is proposed, based solely on the solvent molecular structure and relying on the "COnductor-like Screening MOdel for Real Solvents" (COSMO-RS), in whic...

A new surgical classification for temporomandibular joint disorders.

A simple classification that also guides treatment.

Accuracy and cut-off point selection in three-class classification problems using a generalization of the Youden index.

We study properties of the index J(3), defined as the accuracy, or the maximum correct classification, for a given three-class classification problem. Specifically, using J(3) one can assess the discr...