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Search Results for "Paediatric Study Teriflunomide"

18:37 EDT 30th March 2017 | BioPortfolio

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SERAPHIN study

SERAPHIN - STUDY WITH ENDOTHELIN RECEPTOR ANTAGONIST IN PULMONARY ARTERIAL HYPERTENSION TO IMPROVE CLINICAL OUTCOME. SERAPHIN (Study with an Endothelin Rece...

KIACTA

KIACTA™ (also known as eprodisate) is an orally bioavailable small molecule intended for the treatment of AA amyloidosis, an orphan indication that results from long-standing inflammatory cond...

Viruses

A virus is a small infectious agent that can replicate only inside the living cells of organisms. Virus particles (known as virions) consist of two or three parts: the genetic material made from eit...

Hepatitis C

Most hepatitis C virus (HCV) infected individuals seeking treatment are chronically infected. Treatment goal is to achieve a sustained virological response (SVR), which is the absence of serum HCV R...

Spirometry Test

The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...

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Novartis posts 82% remission rate in CAR T paediatric study

Novartis has released the results of its global, paediatric study of the treatment of leukaemia in children and young adults with CAR T therapy. The study found that the 82% of patients (41 patients o...

[Articles] Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration

We have created a unified global approach to risk stratification in children with hepatoblastoma on the basis of rigorous statistical interrogation of what is, to the best of our knowledge, the larges...

Paediatric rheumatic diseases: Navigating the transition from paediatric to adult care

New guidelines from EULAR and the Paediatric Rheumatology European Society recommend a set of quality standards for the care of young adults with childhood-onset rheumatic diseases during their transf...

CD47 antibody fights paediatric brain tumors in preclinical testing

Five types of paediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumours without hurting healthy brain cells, according to a ...

New treatment recommendations for a high-risk paediatric leukaemia

Research led by St. Jude Children's Research Hospital has identified three genetic alterations to help identify high-risk paediatric patients with acute megakaryoblastic leukaemia (AMKL) who may benef...

BRIEF-Genfit initiates paediatric NAFLD/NASH program in Europe

* Genfit initiates paediatric NAFLD/NASH program in Europe further to the approval of elafibranor's paediatric investigation plan by the EMA Source text for Eikon: Further company coverage: (Gdyn...

Advances in paediatric ALL

Dr Locatelli speaks with ecancer about the state of care for paediatric ALL. He considers the past, present and future of treatment modalities, with the advent of TKI therapy for a range of patient s...

FDA and EMA to work more closely on paediatric drug regulation

European and US regulators are to move towards a harmonised review of paediatric medicines on either side of the Atlantic, in order to create a more streamlined process. A regulatory conference he...

Matching PubMed Articles

Intracellular CD3+ T-lymphocyte teriflunomide concentration is poorly correlated with and has greater variability than unbound plasma teriflunomide concentration.

Leflunomide's active metabolite teriflunomide inhibits dihydro-oroate dehydrogenase (DHODH), an enzyme essential to proliferation of T-lymphocytes. As teriflunomide must reach the target site to have ...

The efficacy of teriflunomide in patients who received prior disease-modifying treatments: Subgroup analyses of the teriflunomide phase 3 TEMSO and TOWER studies.

Teriflunomide is a once-daily oral immunomodulator approved for relapsing-remitting multiple sclerosis (MS). The objective of this post hoc analysis of the phase 3, pooled TEMSO (NCT00134563) and TOWE...

Inequality of Paediatric Workforce Distribution in China.

Child health has been addressed as a priority at both global and national levels for many decades. In China, difficulty of accessing paediatricians has been of debate for a long time, however, there i...

Influence of postcode on paediatric admissions in Seville.

The postcode (where the home is situated) is an indicator of socioeconomic status and is associated with morbidity, mortality, and the use of health services. The aim of this study was to analyse its ...

Testicular atrophy following paediatric primary orchidopexy: A prospective study.

With the Nordic consensus statement advocating orchidopexy at an earlier age, the present study sought to investigate the outcomes of primary paediatric orchidopexy at a tertiary UK centre.

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