Search Results for "Pancreatic Cancer Cd133"
Original Source: Enhanced cell migration and invasion of CD133(+) pancreatic cancer cells cocultured with pancreatic stromal cells.
BACKGROUND:: Recently, cancer stem cells have been reported as a new therapeutic target in pancreatic cancer as well as other cancers, but the specific role of these cells is unknown. METHODS:: The authors investigated the functional roles of CD133(+) cells, 1 of the putative cancer stem cell candidates in pancreatic cancer. CD133 expression was assessed in human pancreatic cancer and cancer cell lines by quantitative real-time reverse transcriptase polymerase chain reaction and flow cytometry. Next, they c...
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The pancreas secretes a number of important hormones into the digestive tract and the blood stream. Cancers are most commonly exocrine than endocrine (neuroendocrine) tumors. Functional tumors secre...
Epithelial cell adhesion molecule EpCAM CD326
Epithelial cell adhesion molecule (EpCAM; CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian,...
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Striving to increase survival rates in pancreatic cancer in the UK
Alex Ford, CEO of Pancreatic Cancer UK, shares with us the aims of the charity and highlights how we can raise awareness of pancreatic cancer. Pancreatic cancer is the ninth most common cancer in th...
"Pancreas In A Dish" Will Show How Pancreatic Cancer Forms
A tiny, living 3-D organ model of pancreatic ducts has been created by researchers in Toronto to help them understand pancreatic cancer, which is one of the deadliest yet least understood of all cance...
"Pancreas In A Dish" Helps Scientists Study How Pancreatic Cancer Forms
A tiny, living 3-D organ model of pancreatic ducts has been created by researchers in Toronto to help them understand pancreatic cancer, which is one of the deadliest yet least understood of all cance...
Pancreatic cancer: FDG-PET is not useful in early pancreatic cancer diagnosis
Better tools for early detection and accurate staging of pancreatic cancer are needed. The role of 18F-fluorodeoxyglucose (FDG)-PET in this setting is controversial. The results of a large retrospecti...
In Pancreatic Cancer Model Nerve Growth Factors Elevated
Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancr...
New Combo Treatment Offers Hope For Pancreatic Cancer Patients
Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progr...
Light Shed On How Pancreatic Cancer Begins
A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages. Research led by scientists at...
Molecular marker from pancreatic 'juices' helps identify pancreatic cancer
Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis—two disorders that are difficult to tell apart. A molecular marker obta...
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BACKGROUND:: Recently, cancer stem cells have been reported as a new therapeutic target in pancreatic cancer as well as other cancers, but the specific role of these cells is unknown. METHODS:: The au...
Pancreatic cancer is a lethal disease because of invasion and early metastasis. Although CD133, a marker of cancer stem cells (CSCs) in a variety of solid tumors, has been studied in recent decades, i...
Although CD133 has been reported to be a promising colon cancer stem cell marker, the biological functions of CD133(+) colon cancer cells remain controversial. In the present study, we investigated th...
CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality?
CD133, a member of the prominin family, is found in a variety of tissues with at least three variants. The function of CD133 is not well understood, but its expression is subject to changes in the mic...
CD133+ liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma.
CD133 is a cancer stem-cell (CSC) marker associated with radioresistance and chemoresistance in various cancers. In the present study, CD133-expressing liver cancer cells following radiation exposure...
