ATX-MS-1467 for patients with multiple sclerosis (MS)

ATX-MS-1467 is a novel treatment that was developed with the aim of working with the immune system to treat the underlying cause of disease rather than just treating the symptoms or suppressing the...

Clinical Approvals - news, views, reports and blogs

Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and eff...

Facebook - BioPortfolio Pages

BioPortfolio has launched a number of Facebook pages to allow our visitors to keep track with latest news, published paper and clinical trials by lead biotechnology and healthcare topics:- &nbs...

Xofigo (radium-223 dichloride)

New treatment for castration-resistant prostate cancer (CRPC) patients with bone metastases. Xofigo shown in a pivotal phase III trial to significantly improve overall survival. Xofigo® with...

Vitamin E Toxicity

Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...

Add-on pantoprazole may boost glycemic control in diabetics

NEW YORK (Reuters Health) - The proton pump inhibitor (PPI) pantoprazole seemed to help type 2 diabetics on oral therapy in a small study from India.

[Hanmi] grants [Amneal] exclusive US distribution rights to esomeprazole strontium

South Korean therapeutics developer [Hanmi Pharmaceutical Co. Ltd.] has licensed generics company [Amneal Pharmaceuticals LLC] exclusive rights to distribute its esomeprazole strontium delayed-release...

Pfizer licenses OTC form of AstraZeneca's heartburn drug Nexium

AstraZeneca granted Pfizer the right to market an over-the-counter version of heartburn treatment Nexium, or esomeprazole.  -More- White Paper: Improving Total Cost of Ownership with EQMS Co...

What Is Nexium (Esomeprazole Magnesium)?

Nexium, generic name esomeprazole, is a proton-pump inhibitor used for the treatment of GERD (gastroesophageal reflux disease), duodenal ulcer disease, and erosive esophagitis. Proton-pump inhibitors...

Human medicines European Public Assessment Report (EPAR): Somac Control, pantoprazole, Revision: 4, Authorised

Human medicines European Public Assessment Report (EPAR): Controloc Control, pantoprazole, Revision: 3, Authorised

Human medicines European Public Assessment Report (EPAR): Pantozol Control, pantoprazole, Revision: 3, Authorised

Human medicines European Public Assessment Report (EPAR): Pantoloc Control, pantoprazole, Revision: 5, Authorised

Differential inhibitory effects of proton pump inhibitors on the metabolism and antiplatelet activities of clopidogrel and prasugrel.

The interaction between proton pump inhibitors (PPIs) and clopidogrel/prasugrel were investigated. The IC(50) values of omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on the met...

Ventricular bigeminy associated with voriconazole, methadone and esomeprazole.

Case We report a case of ventricular bigeminy with concomitant administration of methadone, voriconazole and esomeprazole in a Caucasian woman aged 26 with acute lymphoblastic leukaemia. Plasma concen...

Pharmacodynamic interaction between pantoprazole and vecuronium at neuromuscular junction.

1 The effect of pantoprazole on vecuronium-induced neuromuscular blockade in in vivo has not been clearly defined. In this study, we demonstrate that chronic administration, but not acute administra...

A Multicenter, Randomized, Open-Label, Pharmacokinetics and Safety Study of Pantoprazole Tablets in Children and Adolescents Aged 6 Through 16 Years With Gastroesophageal Reflux Disease.

Children with gastroesophageal reflux disease (GERD) may benefit from gastric acid suppression with proton pump inhibitors such as pantoprazole. Effective treatment with pantoprazole requires correct...

Inhibitory effects of intravenous lansoprazole 30 mg and pantoprazole 40 mg twice daily on intragastric acidity in healthy Chinese volunteers: A randomized, open-labeled, two-way crossover study.

Background: Until now there has been no study that directly compares the effect of lansoprazole and pantoprazole administered intravenously on intragastric acidity. The aim of this study is to compare...