The Top 100 Pharmaceutical Companies

The Top 100 Pharmaceutical Companies, determined by total sales in 2011 - see below for 2010 and  2009: They are listed in descending order with the sales in 2011 in $ million; Pfizer ...

FDA approves Perrigo ANDA for generic Duac gel

Perrigo Company has received final FDA approval for its abbreviated new drug application (ANDA) for clindamycin phosphate and benzoyl peroxide 1.2% / 5% topical gel, the generic equivalent of Duac gel...

Epiduo adapalene/benzoyl peroxide regulatory update

Duac clindamycin/benzoyl peroxide regulatory update

Perrigo Receives FDA Approval and Commences Launch of Clindamycin Phosphate and Benzoyl Peroxide 1.2% / 5% Gel

ALLEGAN, Mich., June 27, 2012 /PRNewswire/ -- Perrigo Company (Nasdaq: PRGO;TASE) today announced that it has received final approval from the U.S. Food and Drug Administration for its abbreviate...

Sol-Gel announces positive results from E-BPO phase II study

Sol-Gel Technologies has announced positive results from encapsulated benzoyl peroxide (E-BPO) phase II trial conducted in the US.

Watson seeks FDA approval to market Epiduo Gel for severe acne

Watson Pharmaceuticals, Inc. today confirmed that its subsidiary, Watson Laboratories, Inc., filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration seeking approva...

Regulatory Update -- Stiefel, a GSK company announces a new, alternate, fixed-dose combination of Duac® (clindamycin 1% and benzoyl peroxide 3%) gains positive recommendation for approval in Europe

RESEARCH TRIANGLE PARK, North Carolina, March 4, 2013 /PRNewswire/ -- Stiefel, a GSK (LSE:GSK) company, announced today that it has received positive recommendation by MHRA (Medicine and Healthcar...

Perrigo Acquires Eye-Care Portfolio from Fera

Perrigo Co. said Monday that it bought the ophthalmic ointment and solution portfolio of Fera Pharmaceuticals LLC for $93 million in cash. Perrigo has been looking for an ophthalmic deal as part of it...

Topical dose justification: benzoyl peroxide concentrations.

Abstract Background: Benzoyl peroxide (BPO) is widely utilized in acne treatment as an alternative to antibiotics against which Propionibacterium acnes becomes more resistant. Objective: This overv...

Benzoyl peroxide (BPO)-promoted oxidative trifluoromethylation of tertiary amines with trimethyl(trifluoromethyl)silane.

The benzoyl peroxide (BPO)-promoted oxidative functionalization of tertiary amines under transition-metal-free reaction conditions was developed. Various 1-trifluoromethylated tetrahydroisoquinoline d...

Pd-catalyzed intermolecular C-h amination with alkylamines.

C-H amination of N-aryl benzamides with O-benzoyl hydroxylamines has been achieved with either Pd(II) or Pd(0) catalysts. Furthermore, we demonstrate that secondary amines can be directly used with be...

Association between allergy to benzoyl peroxide, vitiligo and implantation of a cemented total knee joint prosthesis : Is there a connection?

Allergies against bone cement or bone cement components have been well-described. We report on a 63-year-old patient who presented with progressive vitiligo all over the body after implantation of a c...

A new resorufin-based spectroscopic probe for simple and sensitive detection of benzoyl peroxide via deboronation.

A new resorufin-based probe is developed, which exhibits a rapid and sensitive color and a fluorescence off-on response to benzoyl peroxide (BPO) in aqueous media containing 10% ethanol via deboronati...