Nonalcoholic Steatohepatitis NASH

Nonalcoholic steatohepatitis or NASH is a common, often “silent” liver disease. It resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major featu...

Pfizer

Pfizer is a global pharmaceutical company, the largest in world based on annual sales.  In 2009, annual sales were worth $45,448m. Pfizer spend £550m on R&D in the UK alone, and have...

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NASH: A useful mouse model of NASH

Hope for future treatments for Common Liver Disease with new opossum model

Scientists at Texas Biomed have developed the laboratory opossum as a new animal model to study the most common liver disease in the nation - afflicting up to 15 million Americans - and for which ther...

Ira Nash, MD, Named Executive Director of the North Shore-LIJ Medical Group

Great Neck, NY (PRWEB) June 10, 2013 The North Shore-LIJ Health System today announced the appointment of Ira Nash, MD, as senior vice president and executive director of the North Shore-LIJ Medica...

From Steatosis to NASH: Is NAFLD a Spectrum?

Although steatosis and NASH are viewed as 2 histological subtypes of NAFLD, are the 2 conditions really distinct, not only from a histological but also from a pathophysiological standpoint? Alimenta...

Mochida's top seller Epadel hits snag in planned NASH indication

Mochida's Epadel (ethyl icosapentate) has failed to show benefits over placebo in the treatment of non-alcoholic steatohepatitis (NASH), marking a setback for the fish oil-derived prescription produc...

Why Aren’t More People Filling Their Prescriptions?

Ellen Nash, 20, a college sophomore, had been taking a generic asthma drug for a year, with a copay of just $5, when her doctor decided to switch her to a newer drug. He wanted to put Nash on the diff...

Study demonstrates accuracy of non-invasive test for NASH diagnosis

A Chinese study presented at the International Liver CongressTM 2013 has demonstrated the accuracy of a non-invasive test for non-alcoholic steatohepatitis (NASH) diagnosis.

DSM completes acquisition of Kensey Nash and strengthens its biomedical business

Royal DSM, the global Life Sciences and Materials Sciences company, today announced that it has successfully completed the acquisition of Kensey Nash, through the merger of its subsidiary Biomedical A...

The relevance of Nash equilibrium to psychiatric disorders.

In game theory, the word 'game' is used to describe any interdependence between interacting parties, and the Nash equilibrium is a prominent tool for analysing such interactions. I argue that the conc...

Pathophysiological analysis of nonalcoholic fatty liver disease by evaluation of fatty liver changes and blood flow using xenon computed tomography: can early-stage nonalcoholic steatohepatitis be distinguished from simple steatosis?

INTRODUCTION: Effective noninvasive tests that can distinguish early-stage nonalcoholic steatohepatitis (NASH) from simple steatosis (SS) have long been sought. Our aim was to determine the possibilit...

NASH: A useful mouse model of NASH.

Serum Immunoglobulin A Concentration Is an Independent Predictor of Liver Fibrosis in Nonalcoholic Steatohepatitis Before the Cirrhotic Stage.

BACKGROUND AND AIMS: The similarity of alcoholic liver disease and nonalcoholic steatohepatitis (NASH) in terms of pathogenic mechanisms suggests that immunoglobulin A (IgA) may play an important role...

TNF-α messenger ribonucleic acid (mRNA) in patients with nonalcoholic steatohepatitis.

tumor necrosis factor (TNF)-α plays a significant role in the pathogenesis of nonalcoholic steatohepatitis (NASH). A few studies have confirmed high TNF-α plasma protein levels in patients with NASH...