Search Results for "Phase I Study Of Methotrexate For Hiv Infection"
Original Source: Effects of Hydroxychloroquine on Immune Activation and Disease Progression Among HIV-Infected Patients Not Receiving Antiretroviral Therapy: A Randomized Controlled Trial.
CONTEXT Therapies to decrease immune activation might be of benefit in slowing HIV disease progression. OBJECTIVE To determine whether hydroxychloroquine decreases immune activation and slows CD4 cell decline. DESIGN, SETTING, AND PATIENTS Randomized, double-blind, placebo-controlled trial performed at 10 HIV outpatient clinics in the United Kingdom between June 2008 and February 2011. The 83 patients enrolled had asymptomatic HIV infection, were not taking antiretroviral therapy, and had CD4 cell counts gr...
Matching Channels
SERAPHIN - STUDY WITH ENDOTHELIN RECEPTOR ANTAGONIST IN PULMONARY ARTERIAL HYPERTENSION TO IMPROVE CLINICAL OUTCOME. SERAPHIN (Study with an Endothelin Rece...
Matching News
Infliximab Plus Methotrexate for Psoriatic Arthritis
How superior is infliximab plus methotrexate over methotrexate alone for psoriatic arthritis patients? Annals of the Rheumatic Diseases
Methotrexate use linked to reduced mortality in RA
(HealthDay)—Use of methotrexate for one year or more is associated with a reduction in the risk of mortality for patients with rheumatoid arthritis (RA), according to a study published online Oct. 8...
Chelsea Therapeutics International Ltd. (NASDAQ:CHTP) fell $0.61 (31%) to $1.34 on Thursday after CH-4051 missed the co-primary endpoints vs. methotrexate in a Phase II trial to treat rheumatoid arthr...
Comparison Study Of Rheumatoid Arthritis Drugs Abatacept And Adalimumab
Data from one of the few head-to-head trials in rheumatoid arthritis (RA) presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism, demonstrates that at one year, 64.8% o...
Methotrexate and Etanercept for Plaque Psoriasis
This study evaluated etanercept plus methotrexate vs. etanercept monotherapy in patients with moderate to severe plaque psoriasis. The British Journal of Dermatology
Ablynx [Euronext Brussels: ABLX] has announced that its anti-IL-6R Nanobody, ALX-0061, met the efficacy endpoint of a significant improvement in key indicators of disease activity at the 12 week inter...
Conventional or reduced doses of etanercept with methotrexate in patients with moderately active rheumatoid arthritis more effectively maintain low disease activity than does methotrexate alone after...
Lilly-Incyte's baricitinib yields encouraging results in RA trial
A Phase IIb study showed that 76% of active rheumatoid arthritis patients on methotrexate who received Eli Lilly and Co. -More-
Matching PubMed Articles
Udp-Glucuronosyltransferase 1a6 Overexpression In Breast Cancer Cells Resistant To Methotrexate.
Methotrexate is a chemotherapeutic agent used in breast cancer treatment, but the occurrence of resistance limits its therapeutic use. A microarrays analysis between sensitive and methotrexate resista...
Protein-templated gold nanoclusters as fluorescence probes for the detection of methotrexate.
In this contribution, bovine serum albumin stabilized gold nanoclusters as novel fluorescent probes were successfully utilized for the detection of methotrexate for the first time. Our prepared gold n...
OBJECTIVES: Accurate communication of information concerning the risks and benefits of medications is essential for adherence and patient safety. A diverse array of information and sources makes it di...
On the basis of the documented racial disparities in ectopic pregnancy incidence and mortality we hypothesized that African-American women with ectopic pregnancy would be more likely than white women...
BACKGROUND: Patients with ulcerative colitis often receive thiopurines as immunomodulators (IMs) to maintain remission and avoid corticosteroids. If unresponsive or intolerant to these agents, patient...
