Drug Approvals

In order to become availible to pateints, drugs need to undergo a number of phases of clinical trials to test their efficacy and safty and to then be authorised by the drug approval organistion in e...

Bcl-2 Antisense Drug

CMV Antisense Drug

Drug Discovery - news, views, blogs and reports

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identi...

Minimizing drug interactions

FDA approves first drug to prevent HIV infection

The US Food and Drug Administration this week approved for the first time a drug for use in the prevention of HIV infection. The drug, Truvada, is one of the most commonly used components of an......

Medivation files NDA for prostate cancer drug enzalutamide

US drug developer Medivation (Nasdaq: MDVN) says it has submitted a New Drug Application to the US Food and Drug Administration for its investigational cancer drug enzalutamide (formerly MDV3100).

Drug delivery

Drug delivery is the method or process of administering a drug to achieve a therapeutic effect. Drug delivery technologies modify drug release profile, absorption, distribution and elimination for the...

FDA staff says NPS Pharma's bowel drug needs no safety restrictions

(Reuters) - U.S. drug reviewers found three serious concerns related to NPS Pharmaceuticals Inc's experimental drug for short bowel syndrome, but said they did not think the drug needed to be restrict...

Epigenetic-Dependent Regulation of Drug Metabolism

Gene expression encoding drug transporters and drug-metabolizing enzymes are highly variable between individuals, leading to large variations in drug response. How does epigenetics factor in? Pharma...

FDA Approves New Drug for Obesity

It is common knowledge that obesity has become an epidemic in the United States. Drugs used to treat the condition are in severely short supply, however. The Food and Drug Administration just approved...

AstraZeneca, Ironwood partner on IBS drug in China

British drug giant AstraZeneca PLC and a small U.S. drug developer, Ironwood Pharmaceuticals Inc., said Tuesday that they are teaming up to develop and then market Ironwood's new drug for irritable bo...

News Summary: FDA stops Idenix drug testing

SIDELINED: Hepatitis C drug developer Idenix Pharmaceuticals Inc. said Thursday that the Food and Drug Administration halted trials of its most advanced drug because of concerns about its effects on p...

Selective pretreatment and determination of phenazopyridine using an imprinted polymer-electrospray ionization ion mobility spectrometry system.

In this research, selective separation and determination of phenazopyridine (PAP) is demonstrated using molecular imprinted polymer (MIP) coupled with electrospray ionization ion mobility spectrometry...

Managing the adverse effects of radiation therapy.

Nearly two thirds of patients with cancer will undergo radiation therapy as part of their treatment plan. Given the increased use of radiation therapy and the growing number of cancer survivors, famil...

Food and Drug Administration's Obesity Drug Guidance Document: A Short History.

Drug transporters in drug efficacy and toxicity.

Drug transporters are now widely acknowledged as important determinants governing drug absorption, excretion, and, in many cases, extent of drug entry into target organs. There is also a greater appre...

Emerging In vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions.

Drug-drug interactions comprise a significant cause of morbidity and mortality worldwide as they may lead to adverse clinical events, result in decrease/inactivation of the therapeutic effect of a dru...