Water and Sodium Balance

Radioactive sodium iodine 131I radioiodine

Types of laxatives

Laxatives are medicines that relieve constipation (difficulty with bowel movements). They are a popular type of over-the-counter remedy. They can also be prescribed for conditions that could get wor...

KYNAMRO

KYNAMRO (mipomersen sodium) injection is an oligonucleotide inhibitor of apolipoprotein B-100 synthesis indicated as an adjunct to lipid-lowering medications and diet to reduce low density lipoprote...

Singulair

Singulair, the brand name for montelukast sodium, is produced by Merck & Co., Inc. Its annual sales in 2009 were $3m, ranking it 7th in the world. Singulair acts by blocking leukotrienes, to r...

US FDA approves ANDA for Mylan's Phenytoin Chewable Tablets

Mylan's subsidiary Mylan Pharmaceuticals has received final approval from the US Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Phenytoin Chewable Tablets USP,...

Population-Based Efforts May Be Necessary To Lower Excessive Dietary Sodium Intake

Recent studies that examine links between sodium consumption and health outcomes support recommendations to lower sodium intake from the very high levels some Americans consume now, but evidence from...

Cutting Salt Could Save Hundreds Of Thousands Of Lives

Reducing the amount of salt the U.S. population consumes could save hundreds of thousands of American lives, according to recent research published in the journal Hypertension. Salt is a chemical comp...

Sodium Rhythms In The Body Revealed By Space-Simulation Study

Maintaining the right sodium levels in the body is crucial for controlling blood pressure and ensuring proper muscle function. Conventional wisdom has suggested that constant sodium levels are achieve...

Interventions To Reduce Dietary Salt Supported By Canadians

Many Canadians are concerned about dietary sodium and welcome government intervention to reduce sodium intake through a variety of measures, including lowering sodium in food, and education and awaren...

Helping Consumers Reduce Sodium Intake

Americans, both adults and children, consume much too much sodium, which can raise blood pressure and increase the risk of heart disease. FDA is working on a number of fronts to help consumers manage...

Life-Saving Reduction In Sodium Consumption

Less sodium in the U.S. diet could save 280,000 to 500,000 lives over 10 years, according to new research in the American Heart Association journal Hypertension. Using computer simulations and models...

Studies support population-based efforts to lower excessive dietary sodium intakes

(National Academy of Sciences) Recent studies that examine links between sodium consumption and health outcomes support recommendations to lower sodium intake from the very high levels some Americans...

Two percent topical phenytoin sodium solution in treating pyoderma gangrenosum: a cohort study.

Oral phenytoin is an extensively used medicine for the treatment of convulsive disorders. Topical phenytoin has also been used for various types of ulcers. To determine the effectiveness of 2% topical...

Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs.

KuKanich, B., Nauss, J. L. Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs. J. vet. Pharmacol. Therap. doi: 10.1111/j.1365-2885.2011...

Population pharmacokinetics of phenytoin after intravenous administration of fosphenytoin sodium in pediatric patients, adult patients, and healthy volunteers.

PURPOSE: We performed a population pharmacokinetic analysis of phenytoin after intravenous administration of fosphenytoin sodium in healthy, neurosurgical, and epileptic subjects, including pediatric...

Effect of aceclofenac on pharmacokinetic of phenytoin.

Aceclofenac is presently most commonly prescribed analgesic for chronic pain and inflammatory conditions. In clinical practice, phenytoin and aceclofenac are used in a chronic condition of generalized...

Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in rats.

P-gp is playing significant role in the development of the drug resistance by altering the absorption of drugs. The objective of present investigation was to study the effect of verapamil on the pharm...