Search Results for "Pituitary Gland And Chronic Trauma"
Original Source: Anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury patients and the influence on functional outcome.
Objective: The objective of this study is to determine the prevalence of anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury (TBI) patients. The investigation of a relationship between pituitary hormonal status and body mass index (BMI) in TBI patients by observing changes in BMI was conducted as well as an assessment of whether there is a difference in functional outcome related to anterior pituitary dysfunction in TBI patients. Methods: Forty-five TBI patients and 30 normal...
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Pituitary gland: New pathways in the pathogenesis of pituitary adenomas
Acromegaly is caused by a growth-hormone-secreting pituitary adenoma. Mutations in the AIP gene predispose patients to young-onset pituitary adenomas that are resistant to somatostatin analogue therap...
Mouse Model Sheds Light On Human Pituitary Disorder
Pituitary hypoplasia, or incomplete growth of the pituitary gland, causes hormone deficiencies in humans. One form is caused by a mutation in the SOX2 gene, resulting in eye abnormalities, short statu...
SOX2 mouse model sheds light on human pituitary disorder
Pituitary hypoplasia, or incomplete growth of the pituitary gland, causes hormone deficiencies in humans. One form is caused by a mutation in the SOX2 gene, resulting in eye abnormalities, short statu...
Reprogramming cell identity in the pituitary gland
(Institut de recherches cliniques de Montreal) A team of researchers at the IRCM, supervised by Dr. Jacques Drouin, reprogrammed the identity of cells in the pituitary gland and identified critical me...
A team of researchers reprogrammed the identity of cells in the pituitary gland and identified critical mechanisms of epigenetic cell programming. The discovery could eventually lead to new pharmacolo...
Discovery By IRCM Researchers Could Lead To New Treatments For Cushing's Disease
A team of researchers at the IRCM, supervised by Dr. Jacques Drouin, reprogrammed the identity of cells in the pituitary gland and identified critical mechanisms of epigenetic cell programming. This i...
Pituitary tumors may lead to glaucomatous changes
Certain tumors of the pituitary gland are associated with glaucomatous abnormalities of the optic nerve head, such as enlarged beta zone, an international research team reports.Taken from Medwire news...
Pituitary gland: ESRP1—a regulator of epithelial–mesenchymal transition in somatotroph adenomas?
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Stereological techniques using point counting and planimetry have been used to estimate pituitary gland volume. However, many studies have estimated pituitary gland volume by the mathematical approach...
Morphometry of the pituitary gland and hypothalamus in long-term survivors of childhood trauma.
PURPOSE: Chronic pituitary dysfunction is increasingly recognized as a sequela of traumatic brain injury (TBI). Our aim was to rule out any late morphometric changes of the pituitary gland and hypotha...
The pituitary gland is crucially important in the function of the endocrine axis. So far, antenatal depiction of the pituitary gland was possible only using magnetic resonance imaging. We describe ant...
In the anterior pituitary gland, folliculo-stellate cells and five types of hormone-producing cells are surrounded by an extracellular matrix (ECM) essential for these cells to perform their respectiv...
We investigated the effects of lipopolysaccharide (LPS)-induced endotoxemia on the expression of aquaporin-4 (AQP4) in the rat anterior pituitary gland, using the real-time polymerase chain reaction a...
