Search Results for "Plasmid Borne Keratinases"
Original Source: Key determinants affecting sheep wool biodegradation directed by a keratinase-producing Bacillus subtilis recombinant strain.
OVAT (one variable at a time) approach was applied in this study to screen the most important physicochemical key determinants involved in the process of sheep wool biodegradation. The process was directed by a keratinase-producing Bacillus subtilis DB 100 (p5.2) recombinant strain. Data indicate that, sheep wool could be degraded efficiently in cultures incubated at 30 degrees C, with initial pH of 7 with agitation at 150 rpm. Two times autoclaved alkali treated and undefatted chopped sheep wool is more ac...
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Plasmid Land: The Plasmid Cloning Game
When the average person asks, “What is a plasmid?” we sometimes struggle to give them a basic answer. Plasmids are circular fragments of double-stranded DNA that can replicate independen...
It is estimated that about 100 million cases of infection by Dengue virus occur each year and that nearly half the world’s population is at risk of Dengue virus infection. At present, no vacci...
ImuXen® is a liposomal technology platform designed to improve the delivery and effectiveness of DNA, protein and polysaccharide vaccines. Proof of concept preclinical studies with a number of...
Clinical Approvals - news, views, reports and blogs
Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and eff...
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Plasmid partition: sisters drifting apart
Studies recapitulating key features of plasmid partitioning in vitro reveal how protein patterning on the bacterial nucleoid directs plasmid positioning and segregation.
Althea, Profectus in Plasmid Production Pact
Althea to provide cGMP plasmid DNA for vaccine development
ParA-mediated plasmid partition driven by protein pattern self-organization
ParA-mediated plasmid partition driven by protein pattern self-organizationIn vitro reconstitution of bacterial plasmid partitioning supports a ‘diffusion-ratchet’ concept, resetting the discussio...
Improved Standard for Immune System Recovery Assay
Monitoring an immune system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation is vital to assessing individual?s recovery status. This technology provid...
A Free Board Game Called Plasmid Land Explains The Basics Of Plasmid Cloning
CAMBRIDGE, Mass., Dec. 3, 2012 /PRNewswire/ --Scientists find that games and graphics help break down complex topics like plasmid cloning. (Photo: http://photos.prnewswire.com/prnh/20121203/PH22695 )...
VGXI, OncoSec partner to produce interleukin-12 plasmid DNA
OncoSec Medical Inc., which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumors, announced today that the Company has entered into an exclusiv...
Chromosomal evolution of Escherichia coli for the efficient production of lycopene
Background: Plasmid-based overexpression of genes has been the principal strategy for metabolic engineering. However, for biotechnological applications, plasmid-based expression systems are not suitab...
Plasmid Useful in Transplantation Therapy for Age-Related Eye Disease
Researchers have developed a green fluorescent protein (GFP) based plasmid that can be used to detect differentiated retinal pigment epithelium (RPE) cells. RPE is a layer of cells located behind the...
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Revisiting microbial keratinases: next generation proteases for sustainable biotechnology.
Keratinases are special proteases which attack the highly recalcitrant keratin substrates. They stand apart from the conventional proteases due to their broad substrate specificity towards a variety o...
Pro-sequences were swapped in cis between keratinases from Bacillus licheniformis (Ker BL) and Bacillus pumilus (Ker BP) to construct Ker ProBP-BL and Ker ProBL-BP, respectively. Expression of these k...
Characterization of Toxin Plasmids in Clostridium perfringens Type C Isolates.
Clostridium perfringens type C isolates cause enteritis necroticans in humans or necrotizing enteritis and enterotoxaemia in domestic animals. Type C isolates always produce alpha toxin and beta toxin...
We have determined the entire DNA sequence of plasmid pKpQIL, the blaKPC-3-carrying plasmid harbored by the carbapenem resistant Klebsiella pneumoniae clone ST 258 in Israel. pKpQIL is a 113,637 bp, s...
Sustained expression of murine interferon (IFN)-γ (Muγ) was found to be effective in preventing tumor metastasis and atopic dermatitis in mouse models. However, our preliminary experiments suggested...
