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Search Results for "Polyethylene Glycol Dna Uptake"

04:55 EDT 22nd May 2013 | BioPortfolio

Original Source: Enhanced cell uptake via non-covalent decollation of a single-walled carbon nanotube-DNA hybrid with polyethylene glycol-grafted poly(l-lysine) labeled with an Alexa-dye and its efficient uptake in a cancer cell.

The use of single-walled carbon nanotubes (SWNTs) for biomedical applications is a promising approach due to their unique outer optical stimuli response properties, such as a photothermal response triggered by near-IR laser irradiation. The challenging task in order to realize such applications is to render the SWNTs biocompatible. For this purpose, the stable and homogeneous functionalization of the SWNTs with a molecule carrying a biocompatible group is very important. Here, we describe the design and syn...

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Mircera methoxy polyethylene glycol-epoetin beta regulatory update

Pharmaceutical Research: The Immunogenicity of Polyethylene Glycol: Facts and Fiction

Type: Review PaperAn increasing number of pegylated therapeutic proteins and drug targeting compounds are being introduced in the clinic. Pegylation is intended to increase circulation time and to red...

Human medicines European Public Assessment Report (EPAR): Mircera, methoxy polyethylene glycol-epoetin beta, Revision: 13, Authorised

Human medicines European Public Assessment Report (EPAR): Mircera, methoxy polyethylene glycol-epoetin beta, Revision: 12, Authorised

More Evidence Found Extolling The Health Benefits Of Green Tea

redOrbit Staff & Wire Reports - Your Universe Online Researchers from the Keimyung University School of Medicine in South Korea have found new evidence supporting green tea’s role as a weight-l...

AAPS PharmSciTech: Plasticizer Effects on Physical–Mechanical Properties of Solvent Cast Soluplus® Films

Type: Original PaperSoluplus® is a novel amphiphilic polymer that has been shown to enhance the solubility and drug dissolution rate of poorly soluble drugs. However, there still is a lack of informa...

Pharmaceutical Research: Moisture Uptake of Polyoxyethylene Glycol Glycerides Used as Matrices for Drug Delivery: Kinetic Modelling and Practical Implications

Type: Original PaperPurposeGelucire 50/13, a polyoxyethylene glycol glyceride mixture, has been widely used in drug delivery, but its moisture uptake behaviour is still poorly understood. In this stud...

Pharmaceutical Research: Oral Delivery of Low Molecular Weight Heparin by Polyaminomethacrylate Coacervates

Type: Original PaperPurposeOral bioavailability of low molecular weight heparin (LMWH) can be achieved by several advanced drug delivery approaches. Here, a new preparation method for coacervates (CAs...

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Exploring the cell uptake mechanism of phospholipid and polyethylene glycol coated gold nanoparticles.

Recently, there has been a lot of interest in using gold nanoparticles (GNPs) for biomedical applications due to their biocompatibility. To increase GNP cell uptake and circulation half-life, and to i...

Modulating water-exchange rates of lanthanide(iii)-containing polyaminopolycarboxylate-type complexes using polyethylene glycol.

We have synthesized a series of Ln(III)-containing polyethylene glycol conjugates and studied the structural and electronic properties of these complexes. These studies demonstrate that polyethylene g...

Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine.

A new conjugate, octreotide-polyethylene glycol(100) monostearate (OPMS), was developed for the enhancement of targeting delivery of hydroxycamptothecine (HCPT) loaded in nanostructured lipid carrier...

Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors.

Iron oxide nanoparticles have found widespread applications in different areas including cell separation, drug delivery and as contrast agents. Due to water insolubility and stability issues, nanopart...

Enhanced cell uptake via non-covalent decollation of a single-walled carbon nanotube-DNA hybrid with polyethylene glycol-grafted poly(l-lysine) labeled with an Alexa-dye and its efficient uptake in a cancer cell.

The use of single-walled carbon nanotubes (SWNTs) for biomedical applications is a promising approach due to their unique outer optical stimuli response properties, such as a photothermal response tri...

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