Search Results for "Polymeric Nanoparticles In Topical Drug Delivery"
Original Source: Polymethacrylate Microparticles Gel for Topical Drug Delivery.
PURPOSE: Evaluating the potentials of particulate delivery systems in topical drug delivery. METHODS: Polymethacrylate microparticles (MPs) incorporating verapamil hydrochloride (VRP) as a model hydrophilic drug with potential topical clinical uses, using Eudragit RS100 and Eudragit L100 were prepared for the formulation of a composite topical gel. The effect of initial drug loading, polymer composition, particularly the proportion of Eudragit L100 as an interacting polymer component and the HLB of the disp...
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Drug Delivery - news, views, blogs
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulat...
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Pharmaceutical Research: Ternary Polymeric Nanoparticles for Oral siRNA Delivery
Type: Original PaperPurposePoor stability and inefficient absorption in the intestinal tract are major barriers confronting oral delivery of siRNA. We aimed to uncover if ternary polymeric nanoparticl...
Type: Original PaperPurposePulmonary administration of polymeric nanoparticle drug delivery systems is of great interest for both systemic and local therapies. However, little is understood about the...
Nanoparticles as a Drug Delivery System
Nanotechnology has the potential to revolutionize drug delivery, but challenges remain. This article summarizes recent developments in the use of nanoparticles as drug delivery systems. Nanomedicine
Type: Original PaperPurposeTo investigate the effects of the particle size and surface coating on the cellular uptake of the polymeric nanoparticles for drug delivery across the physiological drug bar...
Efficacy of drugs boosted by using nanoparticles to target 'powerhouse of cells'
Nanoparticles have shown great promise in the targeted delivery of drugs to cells, but researchers have refined the drug delivery process further by using nanoparticles to deliver drugs to a specific...
Double functionalisation of titanium-based nanoparticles for drug delivery
Scientists in India report the functionalisation of TiO2 nanoparticles with two different biomolecules – tris-(nitrilo tris-acetic acid) and biotin. The biocompatible nanoparticles is non-cytotoxic...
AAPS PharmSciTech: Lyophilized Oral Sustained Release Polymeric Nanoparticles of Nateglinide
Type: Original PaperThe objective of this study is to formulate lyophilized oral sustained release polymeric nanoparticles of nateglinide in order to decrease dosing frequency, minimize side effects,...
Type: Original PaperPurposeTo investigate the percutaneous permeation pathways of cell penetrating peptide modified lipid nanoparticles and oleic acid modified polymeric nanoparticles.MethodsConfocal...
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Azelaic acid (AzA) is used in the treatment of acne. However, side effects and low compliance have been associated with several topical treatments with AzA. Nanotechnology presents a strategy that can...
Immediate topical drug delivery by natural submicron injectors.
Transdermal delivery is an attractive but challenging solution for delivery of drugs. The sea anemone possesses a sophisticated injection system, which utilizes built-in high osmotic pressures. The sy...
Drug loading and release on tumor cells using silk fibroin-albumin nanoparticles as carriers.
Polymeric and biodegradable nanoparticles are frequently used in drug delivery systems. In this study silk fibroin-albumin blended nanoparticles were prepared using the desolvation method without any...
PLGA/polymeric liposome for targeted drug and gene co-delivery.
Chemotherapy is one of the most effective approaches to treat cancers in the clinic, but the problems, such as multidrug resistance (MDR), low bioavailability and toxicity, severely constrain the furt...
Polymethacrylate Microparticles Gel for Topical Drug Delivery.
PURPOSE: Evaluating the potentials of particulate delivery systems in topical drug delivery. METHODS: Polymethacrylate microparticles (MPs) incorporating verapamil hydrochloride (VRP) as a model hydro...
