Anesthesia

Anesthesia is the loss of feeling or sensation in all or part of the body. It may result from damage to nerves or can be induced by an anesthetist (a medical professional) using anesthetics such as...

Fresenius Restricts Propofol Use For Executions

As a result of a campaign by activists to pressure drugmakers to prevent their medications from being used in the US for lethal injections, Fresenius Kabi recently adopted a new policy in which orders...

EEG patterns track propofol effects

Researchers have identified electroencephalogram signatures of changes in consciousness caused by propofol.

PharMEDium Supports Draft Legislation, Efforts to Strengthen Oversight of the Compounding Industry

WASHINGTON, April 26, 2013 /PRNewswire/ -- PharMEDium is encouraged by the progress made today by the twelve bipartisan Members of the Senate Health, Education, Labor, and Pensions (HELP) Committee to...

Propofol Lethal Injections Blocked as Teva and Hospira Re-Enter Market

Both Teva and Hospira have pledged to restrict distribution of propofol as a lethal injection ingredient while production of the drug recommences.

Company bans sale of its drug propofol for the purpose of lethal injections

One of the world’s biggest makers of the anaesthetic propofol has barred its sale for the purpose of lethal injections, as US states that still have the death penalty face growing problems obtaining...

Metabolic patterns of propofol, sevoflurane differ in children

(HealthDay)—For children undergoing routine anesthesia for medically indicated magnetic resonance imaging (MRI), the metabolic signature varies with use of sevoflurane and propofol, according to a s...

Light-Sensitive Moiety Added To Anesthetic Propofol Allowing Control Of Narcotic Effect By Light - May Treat Certain Eye Diseases

In a new study, a light-sensitive moiety has been added to propofol, a commonly used anesthetic, allowing its narcotic effect to be controlled by light. The compound also offers a possible route to th...

Hospira Propofol Injectable Emulsion: Recall - Glass Vial Defect

Audience: Risk Manager, Pharmacy [Posted 08/16/2012]   ISSUE: Hospira and FDA notified healthcare professional of a nationwide recall of three lots of Propofol Injectable Emulsion, 1%, 1g/100 mL...

Minimum infusion rate and hemodynamic effects of propofol, propofol-lidocaine and propofol-lidocaine-ketamine in dogs.

Objective  To evaluate the effects of a constant rate infusion (CRI) of lidocaine alone or in combination with ketamine on the minimum infusion rate (MIR) of propofol in dogs and to compare the hemo...

Possible link between cyclooxygenase-inhibiting and antitumor properties of propofol.

The intravenous anesthetic propofol has a number of well-known nonanesthetic effects, including anti-oxidation and anti-emesis. Another interesting nonanesthetic effect of propofol may be its cyclooxy...

Exploring microsolvation of the anesthetic propofol.

Propofol (2,6-diisopropylphenol) is a broadly used general anesthetic. By combining spectroscopic techniques such as 1- and 2-color REMPI, UV/UV hole burning, infrared ion-dip spectroscopy (IRIDS) obt...

Propofol withdrawal seizures: non-epileptic nature of seizures in a patient with recently controlled status epilepticus.

Seizures or seizure-like phenomena which are mostly convulsive have been observed during the induction, maintenance and withdrawal phases of propofol administration. The nature and mechanism of this p...

Individual Differences in Pharmacokinetics and Pharmacodynamics of Anesthetic Agent Propofol with Regard to CYP2B6 and UGT1A9 Genotype and Patient Age.

Propofol (2,6-diisopropylphenol) is administered intravenously for induction and maintenance of anesthesia; however, cases of progressive myocardial failure (propofol syndrome) related to the use of p...