Pseudomonas aeruginosa Vaccines

Pseudomonas aeruginosa is an opportunistic gram-negative bacteria that lives in soil, water, and even in environments like hot tubs. For most healthy people, this bacteria seldom poses a problem. Pse...

Diseases Caused by Pseudomonas

Pseudomonas and Related Infections

Interleukin-13 Pseudomonas toxin rDNA

Immunotoxins

Immunotoxins are proteins that contain a toxin along with an antibody or growth factor that binds specifically to target cells. Nearly all protein toxins work by enzymatically inhibiting protein syn...

New Vaccine Candidate For Pseudomonas Aeruginosa, The Cause Of Many Hospital-Acquired Infections

Researchers at Brigham and Women's Hospital (BWH) have discovered a new vaccine candidate for the bacterium Pseudomonas aeruginosa taking advantage of a new mechanism of immunity. The study was publis...

Pseudomonas aeruginosa Turns Protein Into a Virulence Factor in One Easy Step

To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining...

Antibiotic Combos in P aeruginosa Bacteremia

An empirical combination of antibiotics is no better than monotherapy for Pseudomonas aeruginosa bloodstream infection, Spanish researchers report. Reuters Health Information

BWH researchers discover new vaccine candidate for Pseudomonas aeruginosa

(Brigham and Women's Hospital) Researchers at Brigham and Women's Hospital have discovered a new vaccine candidate for the bacterium Pseudomonas aeruginosa taking advantage of a new mechanism of immun...

Early Antibiotic Treatment for Pseudomonas in Cystic Fibrosis

Is there a best practice scenario for pseudomonas aeruginosa chronic pulmonary infection in cystic fibrosis? Thorax

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

Michael Bamshad and colleagues report an exome sequencing study of extreme phenotypes to identify genetic variants that modify the risk for chronic Pseudomonas aeruginosa airway infection in individua...

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

Pseudomonas aeruginosa infection of the airways is a major cause of mortality and morbidity for patients with cystic fibrosis (CF). Here, Molin and colleagues discuss how P. aeruginosa infection evolv...

Researchers discover new vaccine candidate for Pseudomonas aeruginosa

Researchers at Brigham and Women's Hospital (BWH) have discovered a new vaccine candidate for the bacterium Pseudomonas aeruginosa taking advantage of a new mechanism of immunity.

Draft Genome Sequence of Pseudomonas aeruginosa Strain ATCC 27853.

Pseudomonas aeruginosa is a common bacterium that can cause disease. The versatility of Pseudomonas aeruginosa enables the organism to infect damaged tissues or those with reduced immunity which cause...

Pseudomonas aeruginosa accentuates epithelial to mesenchymal transition in the airway.

Epithelial to mesenchymal transition has been implicated in the dysregulated epithelial wound repair that contributes to obliterative bronchiolitis after lung transplant. Acquisition of Pseudomonas ae...

Removal and reduction of chromium by Pseudomonas spp. and their correlation to rhamnolipid production.

Chromium removal and its association with rhamnolipid production in Pseudomonas spp. were investigated. Three Pseudomonas spp. isolates (P. aeruginosa 78, P. aeruginosa 99, and P. stutzeri T3) were in...

Complete Genome Sequence of Pseudomonas aeruginosa Lytic Bacteriophage PA1O Which Resembles Temperate Bacteriophage D3112.

A novel Pseudomonas aeruginosa lytic bacteriophage (phage), PA1Ø, was isolated, and its genome was sequenced completely. This phage is able to lyse not only P. aeruginosa but also Staphylococcus aure...

Superinfections in Pseudomonas aeruginosa ventilator-associated pneumonia.

AIM: Data on superinfections in patients with ventilator-associated pneumonia vary, but different pathogens are typically studied as a single category. We studied the incidence of superinfections and...