Anxiety Disorders

Anxiety is caused by stress. It is a natural reaction, and is beneficial in helping us deal with tense situations and pressure. It is deterimental when is becomes an excessive, irrational dread of e...

Bipolar Disorders

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Over half of...

Taiwan Research Finds Mirtazapine Slows Tumor Growth

Taiwan scientists say animal tests show promise for using the antidepressant mirtazapine for slowing the growth of colorectal cancer tumors, thus extending lives.

Use of pharmacogenetics in bioequivalence studies to reduce sample size: an example with mirtazapine and CYP2D6

Veteran, UT Dallas Senior Finds Tools to Battle PTSD

(Medical Xpress) -- There are 1.7 million veterans from Iraq and Afghanistan, and at least a third of them suffer from post-traumatic stress disorder, or PTSD, according to the National Center for PTS...

Expanding the Boundaries of PTSD Treatment

How best to treat posttraumatic stress disorder (PTSD) is a long-standing question. Treatments for PTSD, which began in the late 19th century, have varied greatly. In the current era, numerous PTSD tr...

Stroke survivors with PTSD more likely to avoid treatment

A new survey of stroke survivors has shown that those with post-traumatic stress disorder (PTSD) are less likely to adhere to treatment regimens that reduce the risk of an additional stroke. Researche...

Post-traumatic stress disorder (PTSD) in children: an interview with Donna Gillies

Children with PTSD suffer significant distress or negative impacts on their daily lives. Estimates of the prevalence of PTSD in children and adolescents experiencing trauma are generally very high, at...

Burden of full & subsyndromal PTSD in police who responded to the World Trade Center disaster

(Elsevier Health Sciences) Studies have found that police demonstrated considerable resilience to PTSD compared to other disaster workers after the September 11, 2001 terrorist attack on the World Tra...

Tips for how to help someone with PTSD

You don't have to be a member of the armed forces to have post-traumatic stress disorder (PTSD), but nearly 20 percent of service members deployed to Iraq and Afghanistan reported having symptoms. In...

Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: A randomized controlled trial.

This preliminary study aimed to determine if adding mirtazapine to risperidone might improve negative and cognitive symptoms in schizophrenia. In an 8-week, double-blind clinical trial, we randomly as...

Case series of perimenopausal women with insomnia treated with mirtazapine followed by prolonged-release melatonin add-on and monotherapy.

OBJECTIVES: The sedating antidepressant mirtazapine is used off label for insomnia in perimenopausal women. Despite its apparent efficacy, mirtazapine causes significant increases in appetite and weig...

Differential mechanisms underlie the regulation of serotonergic transmission in the dorsal and median raphe nuclei by mirtazapine: a dual probe microdialysis study.

RATIONALE: Blockade of α2 adrenoceptors and histamine H1 receptors plays important roles in the antidepressant and hypnotic effects of mirtazapine. OBJECTIVES: However, it remains unclear how mirtaza...

Repeated mirtazapine nullifies the maintenance of previously established methamphetamine-induced conditioned place preference in rats.

The atypical antidepressant mirtazapine enhances monoaminergic transmission; thus, mirtazapine therapy may counter the hypo-activation of monoamine systems associated with withdrawal from methamphetam...

Mirtazapine abolishes hyperthermia in an animal model of serotonin syndrome.

Serotonin (5-HT) syndrome is a potentially fatal condition associated with various combinations of serotonergic drugs. Hyperthermia is the most serious symptom of this syndrome. Hyperthermia in 5-HT s...