Search Results for "Pulmozyme Mice"
Original Source: Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Rhinosinusitis disorders are often associated with Cystic Fibrosis. They can restrict quality of life enormously and give cause to repeated ENT surgery. The basic defect in CF is a dysfunction of Chloride channels in exocrine glands, leading to retention of secretions and consecutive chronic inflammation with bacterial superinfections. The prospective placebo controlled cross-over study aims at the evaluation of the efficacy of a nasally inhalation of Pulmozyme with respect to...
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CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. It...
Testicular cancer represents only 1 per cent of all cancers in men, but it is the single biggest cause of cancer-related deaths in men aged 15-35 years in the UK. The causes of testicular cancer and...
Polo-like kinase (Plk) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. Plks form a family of four different proteins that regulates many as...
PKC (protein kinase C) http://www.bioportfolio.com/channels/serine-threonine-protein-kinase-c-pkc is a kinase enzyme and a protein molecule that can change the format of other proteins through chemi...
Top 50 Biopharma Products 2011
Ronald A. Rader, president of the Biotechnology Information Institute provided Contract Pharma a list of the Top 57 Biopharma Products by 2011 revenues (in millions). Mr. Rader subscribes to the sam...
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Chugai Launches Pumozyme In Japan
Chugai Pharmaceuticals began sales of cystic fibrosis treatment Pulmozyme (dornase) in Japan on June 8.
Mice with Lou Gehrig's disease not quite what the doctors ordered
You’ve heard the tale before: Scientists can treat diseases like Alzheimer’s and Lou Gehrig’s in mice, but when those same drugs get to human trials, they fail. Can researchers come up with mice...
Mice show innate ability to vocalize: Deaf or not, courting male mice make same sounds
Scientists have long thought that mice might serve as a model for how humans learn to vocalize. But new research led by scientists at Washington State University-Vancouver has found that, unlike human...
Blood From Youthful Mice Makes Codgers Sharper on Cognitive Tasks | 80beats
Our cognitive abilities tend to decline when we get older, as we have trouble remembering old facts and skills and learning new ones. But a little young blood reverses some ill effects of old age, a...
Wild mice have natural protection against Lyme borreliosis
(University of Zurich) Like humans, mice can become infected with Borrelia. However, not all mice that come into contact with these bacteria contract the dreaded Lyme disease: Animals with a particula...
Researchers find a link between age related memory loss and a specific enzyme in mice
(Medical Xpress) -- A team of researchers working out of the Interdisciplinary Centre for Neurosciences at the University of Heidelberg have found that older mice that had levels of the enzyme DNA met...
Humanized mice for immune system investigation: progress, promise and challenges
This article provides a comprehensive overview of the recent advances in the development and use of humanized mice. The authors consider the remaining challenges and the potential for new advances in...
Singing mice show signs of learning
Guys who imitate Luciano Pavarotti or Justin Bieber to get the girls aren't alone. Male mice may do a similar trick, matching the pitch of other males' ultrasonic serenades. The mice also have certain...
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Adherence to dornase alfa treatment among commercially insured patients with cystic fibrosis.
Abstract Objective: To investigate adherence to dornase alfa therapy among commercially-insured patients with cystic fibrosis (CF) and to examine the impact of adherence on health and economic outcome...
Xrcc2 modulates spontaneous and radiation-induced tumourigenesis in Apcmin/+mice.
XRCC2 has an important role in repair of DNA damage by homologous recombination. Adult Apc(min/+) (min - Multiple Intestinal Neoplasia) mice, wild type or heterozygous for Xrcc2 deficiency, were sham-...
Cage-change interval preference in mice.
Before animal research facilities began using individually ventilated cage (IVC) systems for mice, cages were often changed one or more times per week. When using IVC systems, however, it is standard...
The late effects of radiation on lifespan, lymphocyte proliferation and p53 haplodeficiency in mice.
Purpose: We investigated the effect of irradiation on the lifespan of eight-week-old mice, the number of lymphocytes in bone marrow and the levels of p53 protein expression in the splenocytes. Methods...
Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane.
Summary Granuloma formation is an inflammatory response of the host against invading pathogens or indigestible substances. We generated mesenteric oil granulomas by injecting pristane into the periton...
