Water and Sodium Balance

Synthesis and Release of Thyroid Hormones

Radioactive sodium iodine 131I radioiodine

Drug Delivery - news, views, blogs

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.  Drug delivery technologies are patent protected formulat...

Types of laxatives

Laxatives are medicines that relieve constipation (difficulty with bowel movements). They are a popular type of over-the-counter remedy. They can also be prescribed for conditions that could get wor...

FDA Accepts AcipHex (rabeprazole sodium) Pediatric NDA for Priority Review

FDA approves Eisai's Aciphex Sprinkle for pediatric GERD

The FDA has approved the use of Eisai's Aciphex Sprinkle delayed-release capsules, or rabeprazole sodium, for up to 12 weeks  -More- 

FDA Approves Aciphex Sprinkle (rabeprazole sodium) For Use in Children Ages 1 to 11

Woodcliff Lake, NJ, March 26, 2013 - Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Aciphex Sprinkle Delayed-Release Capsules 5mg and 10mg for the treatment o...

FDA approves Eisai's Aciphex Sprinkle for GERD in children; Inovelon OKed in Japan

Japanese drug major Eisai (TYO: 4523) says that the US Food and Drug Administration has approved Aciphex Sprinkle (rabeprazole sodium) delayed-release capsules for the treatment of gastroesophageal re...

Eisai Granted Additional Six Month U.S. Marketing Exclusivity For Aciphex (Rabeprazole Sodium)

WOODCLIFF LAKE, N.J., Dec. 11, 2012 /PRNewswire/ -- Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) determined that Eisai has met the FDA's Written Request requirements for...

Aciphex Sprinkle delayed-release rabeprazole regulatory update

FDA clears Eisai gastroesophageal reflux disease therapy for children

The US FDA has cleared Eisai's ACIPHEX Sprinkle (rabeprazole sodium) as 12-week gastroesophageal reflux disease (GERD) therapy for use in children between one to eleven years age.

AAPS PharmSciTech: A Novel Multi-Unit Tablet for Treating Circadian Rhythm Diseases

Type: Original PaperThis study aimed to develop and evaluate a novel multi-unit tablet that combined a pellet with a sustained-release coating and a tablet with a pulsatile coating for the treatment o...

An open-label, parallel, multiple-dose study comparing the pharmacokinetics and gastric acid suppression of rabeprazole extended-release with esomeprazole 40 mg and rabeprazole delayed-release 20 mg in healthy volunteers.

Background  Novel rabeprazole extended-release (ER) formulations were developed to provide prolonged gastric acid suppression and potentially improved clinical outcomes in GERD patients. Aim  To e...

Randomised clinical trial: a novel rabeprazole extended release 50 mg formulation vs. esomeprazole 40 mg in healing of moderate-to-severe erosive oesophagitis - the results of two double-blind studies.

Background  Current PPIs may not achieve desired outcomes in some GERD patients due to limited duration of acid inhibition. Aim  To evaluate a novel rabeprazole extended release (ER), which provid...

Effect of CYP2C19 genotypes on the pharmacokinetic/pharmacodynamic relationship of rabeprazole after a single oral dose in healthy Chinese volunteers.

AIMS: To explore the pharmacokinetic/pharmacodynamic relationship of rabeprazole and the role of CYP2C19 genotypes after a single oral dose in healthy Chinese volunteers by a population approach. METH...

Comparison Between the Effect of Omeprazole and Rabeprazole on the Antiplatelet Action of Clopidogrel.

Background: Emerging data suggests that several proton pump inhibitors (PPIs), including omeprazole, might interfere with the antiplatelet action of clopidogrel. However, there is a lack of data for r...

Dual cross-linked pulsatile beads for chronotherapy of asthma: Development and evaluation.

In the present investigation, pulsatile release beads were prepared by ionic gelation technique. Theophylline dual-cross-linked beads were prepared by dropping dispersed phase of theophylline, Delonix...