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Search Results for "Radiobiology Of Re Irradiation"

19:32 EDT 18th May 2013 | BioPortfolio

Original Source: Reirradiation of normal tissues: Preclinical radiobiological data.

Reirradiation represent an unfrequent particular clinical situation. The risk/benefit ratio assessment must be taken into account, considering both clinical and dosimetric aspects. There is a relatively limited amount of preclinical data available to date and clinicians should cautiously perform reirradiations in selected indications. This review summarizes the experimental data available on reirradiation of normal tissues, the consequences on early and late toxicities as well as the intrinsic limitations o...

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Outcomes similar with partial, whole breast irradiation

(HealthDay)—Accelerated partial breast irradiation (APBI) yields five-year clinical outcomes and patterns of failure similar to those achieved with whole breast irradiation (WBI), with excellent thr...

Accelerated Partial Breast Irradiation Using 3-D Conformal External Beam Radiation Therapy is Associated With a Negative Cosmetic Outcome Compared to Whole Breast Irradiation in Some Breast Cancer Patients

BOSTON, Oct. 29, 2012 (GLOBE NEWSWIRE) -- Accelerated partial breast irradiation using 3-D conformal external beam radiation therapy is associated with a negative cosmetic outcome compared to whole b...

Current modalities of accelerated partial breast irradiation

In selected patients with early stage breast cancer, accelerated partial breast irradiation (APBI) has emerged as an alternative treatment option to whole breast irradiation. The authors of this artic...

Comparing Radiation Therapy Regimens for Early-Stage Breast Cancer

The name of the trial is Phase III Randomized Study of Accelerated Hypofractionated Whole-Breast Irradiation and Concurrent Boost versus Standard Whole-Breast Irradiation and Sequential Boost in Patie...

Pharmaceutical Research: Gamma Irradiation of Active Self-Healing PLGA Microspheres for Efficient Aqueous Encapsulation of Vaccine Antigens

Type: Original PaperPurposeTo investigate the effect of γ-irradiation of poly(lactic-co-glycolic acid) (PLGA)/Al(OH)3/0 or 5 wt% diethyl phthalate (DEP) microspheres for active self-healing encapsul...

Childhood cancer survivors who received chest irradiation at risk for pulmonary hypertension in middle age

Researchers have found evidence that chest irradiation may leave some adult survivors of childhood cancer in danger of developing pulmonary hypertension in middle age.

Positioning During Radiotherapy for Breast Cancer—Reply

In Reply: We agree with Dr Sherr that the radiation dose to the left anterior descending (LAD) coronary artery may be relevant to the severity of late effects of heart irradiation in patients with bre...

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

Research from The Cancer Institute of New Jersey shows that an ultra-shortened, accelerated breast irradiation treatment using a balloon device is both logistically achievable and tolerable. The work...

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The effect of ionizing radiation on the homeostasis and functional integrity of murine splenic regulatory T cells.

OBJECTIVE: Radiotherapy affects antitumor immune responses; therefore, it is important to study radiation effects on various compartments of the immune system. Here we report radiation effects on the...

Sensitivity of porcine peripheral blood leukocytes to gamma irradiation in vivo, in vitro and ex vivo.

Purpose: The large white pig is a useful experimental model to compare in vivo, in vitro and ex vivo sensitivity of peripheral blood leukocytes to ionising radiation. Such studies are impossible t...

Small animal radiotherapy research platforms.

Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy research have recently stimulated the development of precise micro-irradiators for small animals such as mice and...

Archiving lessons from radiobiology.

Fundamental mechanisms of DNA radiosensitization: damage induced by low-energy electrons in brominated oligonucleotide trimers.

The replacement of nucleobases with brominated analogs enhances DNA radiosensitivity. We examine the chemistry of low-energy electrons (LEEs) in this sensitization process by experiments with thin fil...

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