Hereditary Nephritis

Lupus Nephritis

Tubulointerstitial Nephritis

Acute tubulointerstitial nephritis ATIN

Chronic tubulointerstitial nephritis CTIN

Lupus nephritis: Implications of the new ACR lupus nephritis guidelines

The American College of Rheumatology recently published guidelines for the screening, treatment, and management of lupus nephritis. How will or should these guidelines impact our current daily practic...

Lupus nephritis: Guidelines for lupus nephritis—more recommendations than data?

Several management guidelines for lupus nephritis have been published this year. All of the guidelines provide clear and consistent recommendations, but although evidence-based, many of the recommenda...

Connective tissue diseases: Management of lupus nephritis—new guidelines revealed

The past decade has seen exciting progress in the management of lupus nephritis, a manifestation of systemic lupus erythematosus that accounts for its major morbidity and mortality. The American Colle...

Lupus nephritis: Urinary CD4+ T cells—a marker of proliferative lupus nephritis

Lupus nephritis: Transatlantic management recommendations compared

In the wake of publication of clinical data for new drugs in the management of lupus nephritis, European rheumatology and renal societies have issued new recommendations for management of this conditi...

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Friedhelm Hildebrandt, Agata Smogorzewska and colleagues show that mutations in the DNA repair gene FAN1 cause karyomegalic interstitial nephritis. These findings implicate deficient DNA damage respon...

B-cell depletion in the treatment of lupus nephritis

Lupus nephritis is the most common severe manifestation of the autoimmune disease systemic lupus erythematosus. Although conventional immunosuppressive therapy can increase survival, this approach is...

FDA withdraws lupus guidance

FDA withdrew 2010 guidance on the development of products to treat systemic lupus erythematosus (SLE) and lupus nephritis caused by SLE. The agency said in a notice that the guidance "no longer reflec...

Tubulointerstitial nephritis and uveitis: report of a rare syndrome.

Tubulointerstitial nephritis and uveitis (TINU) is a rare syndrome with unknown pathogenesis. Data have shown a higher prevalence in female gender. We present a man with tubulointerstitial nephritis a...

Hydatid disease and tubulointerstitial nephritis.

Hydatid disease of the kidney is rare, particularly in the isolated form, and tubulointerstitial nephritis is an extremely uncommon manifestation of renal hydatidosis. Here is the report of a patient...

Tubulointerstitial nephritis with uveitis (TINU) syndrome : A relatively rare rheumatological differential diagnosis with unexplained uveitis.

The tubulo-interstitial nephritis and uveitis (TINU) syndrome, first described in 1975, is a rare disease most probably of autoimmune origin that is characterized by unilateral or bilateral uveitis an...

Lansoprazole-induced acute allergic interstitial nephritis in a renal transplant recipient: a case report.

Drug-induced interstitial nephritis is one of the causes of graft dysfunction in renal transplant recipients. Although commonly implicated as a cause of drug-induced interstitial nephritis in the gene...

Granulomatous interstitial nephritis in chronic lymphocytic leukaemia.

We present a case of granulomatous interstitial nephritis (GIN) associated with chronic lymphocytic leukaemia (CLL). GIN is a rare pathological finding noted in renal biopsy specimens. Furthermore, CL...