SERAPHIN study

SERAPHIN - STUDY WITH ENDOTHELIN RECEPTOR ANTAGONIST IN PULMONARY ARTERIAL HYPERTENSION TO IMPROVE CLINICAL OUTCOME. SERAPHIN (Study with an Endothelin Rece...

Hepatology

Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyle...

Pain

Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in term...

Gynecology

Gynecology is the study of diseases affecting the reproductive organs of women and girls. Add the Gynecology News Channel to your RSS reader;

Viruses

A virus is a small infectious agent that can replicate only inside the living cells of organisms. Virus particles (known as virions) consist of two or three parts: the genetic material made from eit...

Study of Dabigatran in Mechanical Heart Valve Patients Halted

Boehringer Ingelheim is halting the RE-ALIGN trial investigating the use of dabigatran in patients with artificial heart valves. Heartwire

Dabigatran(Pradaxa) in AF: Denmark Experience

And there was no evidence of extra possible risks from dabigatran that had been suggested by some reports. Heartwire

Dabigatran-Treated Patients Safely Undergo AF Ablation

Stopping dabigatran 24 hours prior to radiofrequency catheter ablation for atrial fibrillation and resuming it four hours after the procedure is just as safe and effective as treating patients with un...

2 new papers on dabigatran etexilate (Pradaxa) and intracranial hemorrhage

(Journal of Neurosurgery Publishing Group) The Journal of Neurosurgery Publishing Group is pleased to announce publication of two new studies on dabigatran etexilate (Pradaxa) and intracranial hemorrh...

Dabigatran exposure may RE-LY on genetics

Researchers have found that variants in the ABCB1 and CES1 genes are associated with increased dabigatran plasma levels in patients taking the oral anticoagulant.

Dabigatran Etexilate (Pradaxa) And Intracranial Hemorrhage

The Journal of Neurosurgery Publishing Group is pleased to announce publication of two new studies on dabigatran etexilate (Pradaxa®) and intracranial hemorrhage: one in the Journal of Neurosurgery a...

One Lot of Dabigatran 75 mg Recalled

The voluntary recall affects the 75-mg dose of dabigatran (lot 201900). There are concerns about a manufacturing defect that might affect the integrity of the medication bottles. News Alerts

Dabigatran (Pradaxa) Safe at AF Ablation, vs Warfarin

It may be necessary to withhold only one dose prior to the procedure, a group concludes, having compared their dabigatran strategy with standard warfarin management. Heartwire

Dabigatran: An Oral Novel Potent Reversible Nonpeptide Inhibitor of Thrombin.

Dabigatran is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of throm...

Thromboembolic prophylaxis in orthopedic surgery using dabigatran: an oral direct thrombin inhibitor.

Dabigatran etexilate is a direct thrombin inhibitor that has been in clinical use for the prevention and treatment of venous and arterial thrombosis. Dabigatran allows for oral administration, has a r...

An indirect comparison of dabigatran, rivaroxaban and apixaban for atrial fibrillation.

New oral anticoagulant drugs are emerging as alternatives to warfarin for the prevention of stroke in patients with non-valvular atrial fibrillation. Two agents are direct factor Xa inhibitors (rivaro...

Usefulness of Dabigatran Etexilate as Periprocedural Anticoagulation Therapy for Atrial Fibrillation Ablation.

BACKGROUND: The usefulness of dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF) has been reported. OBJECTIVES: In this study the efficacy and safety of dabiga...

Is dabigatran considered a cost-effective alternative to warfarin treatment: A review of current economic evaluations worldwide.

Abstract Objective Dabigatran was the first of a new generation of anticoagulation drugs for the indication non-valvular atrial fibrillation (AF) to be approved. Evidence show that dabigatran 150mg tw...