Search Results for "Refractory Platelets"
Original Source: Refractory platelet transfusion in a patient with CD36 deficiency due to pseudothrombocytopenia.
Type I CD36 deficiency is defined by the absence of CD36 on both platelets and monocytes. Pseudothrombocytopenia (PTCP) is characterized by a false reduction in the number of platelets in ethylenediaminetetraacetic acid (EDTA)-anticoagulated blood. Here we report a rare case of concomitant CD36 deficiency and PTCP. The patient was a 7-year-old boy who suffered comminuted fractures of the left humeral condyle. In the pre-operative examination, he was found to have thrombopenia and assumed to have idiopathic...
Matching Channels
Matching News
Synthetic blood platelets developed
Synthetic platelets have now been developed. Platelets are the components of blood that allow it to prevent excessive bleeding and to heal wounds. The unique physical and biochemical properties of pla...
Primary immune thrombocytopenia purpura (ITP) is a bleeding disorder in which the immune system generates antibodies that destroy platelets, the cells that cause blood to clot. B cells, immune cells t...
Host response: PF4 — platelets' poison
Platelet factor 4 is the effector molecule used by platelets to kill P. falciparum in infected erythrocytes.
Activated Platelets Linked to Brain Changes After Menopause
Activated platelets are associated with white-matter hyperintensity load and progression in recently menopausal women, new findings show. Medscape Medical News
Synthetic Platelets Could Eventually Be Used For Biomedical Applications
Scientists have succeeded in making synthetic platelets, which after optimization and exhaustive testing, could be suitable for a number...
Study finds protein in platelets fight malaria but only for some people
(Medical Xpress)—Researchers in Australia have found that a protein in platelets found naturally in blood has a protective effect against malaria. In their paper published in the journal Science, th...
Development Of Synthetic Platelets
Synthetic platelets have been developed by UC Santa Barbara researchers, in collaboration with researchers at Scripps Research Institute and Sanford-Burnham Institute in La Jolla, Calif. Their finding...
UCSB creates synthetic platelets for various biomedical applications
Synthetic platelets have been developed by UC Santa Barbara researchers, in collaboration with researchers at Scripps Research Institute and Sanford-Burnham Institute in La Jolla, Calif. Their finding...
Matching PubMed Articles
Refractory platelet transfusion in a patient with CD36 deficiency due to pseudothrombocytopenia.
Type I CD36 deficiency is defined by the absence of CD36 on both platelets and monocytes. Pseudothrombocytopenia (PTCP) is characterized by a false reduction in the number of platelets in ethylenediam...
The role of platelets in defence against pathogens.
Many more platelets are present in healthy mammals than are necessary for routine haemostasis. Thus, they could have other functions. Platelets have many of the attributes of innate immune function in...
Platelets present antigen in the context of MHC class I.
Platelets are most recognized for their vital role as the cellular mediator of thrombosis, but platelets also have important immune functions. Platelets initiate and sustain vascular inflammation in m...
Infusion of mature megakaryocytes into mice yields functional platelets.
Thrombopoiesis, the process by which circulating platelets arise from megakaryocytes, remains incompletely understood. Prior studies suggest that megakaryocytes shed platelets in the pulmonary vascula...
Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum.
Platelets are chief effector cells in hemostasis. In addition, however, their specializations include activities and intercellular interactions that make them key effectors in inflammation and in the...
