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Search Results for "Regional And Cell Type Specific Distribution Of"

18:44 EDT 25th May 2013 | BioPortfolio

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Tumor Antigens

Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates f...

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Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

How metazoans determine where to initiate DNA replication remains mysterious. Now deep sequencing of short nascent strands in different human cell types provides an extensive map of replication origin...

Scaffold coated with long-sugar molecules enhances stem-cell cultures

Stem cells have the unique ability to turn into any type of human cell, opening up all sorts of therapeutic possibilities for some of the world’s incurable diseases and conditions. The problem facin...

New type of cell division discovered

(American Society for Cell Biology) The new type of cell division, which the researchers named klerokinesis, could be an evolutionary failsafe mechanism that rescues a range of cell functions during e...

Host cell protein analysis in therapeutic protein bioprocessing – methods and applications

The analysis of host cell proteins (HCPs) is one of the most important analytical requirements during bioprocess development of therapeutic moieties. In this review, we focus on the comparison of diff...

Roche and BioLamina collaboration on development of novel cell culture systems

Roche and Swedish company BioLamina have formed a research and development agreement to jointly develop new cell culture systems for various applications, including stem cell research. The collaborati...

Cis-regulatory control of corticospinal system development and evolution

SOX transcription factors converge on a cortex-specific enhancer to regulate the dynamic, cell-type-specific expression of Fezf2, a gene necessary for the formation of corticospinal system.

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines

Cell fate: Impede a protein to reprogram

Blockade of just one protein is sufficient to change skin cells into neurons.Several research groups have already converted one cell type to another by adding, for example, specific genes. Now researc...

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Regional ventilation distribution in the first six months of life.

Electrical Impedance Tomography has been used to study regional ventilation distribution in neonatal and paediatric lung disease. Little information has been obtained in healthy newborns and infants....

Regional and cell-type specific distribution of HDAC2 in the adult mouse brain.

The effects of epigenetics on brain functions are not completely understood, but histone deacetylases (HDACs) are known to affect brain function and dysfunction by mediating the acetylation status of...

Regional presentation of hepatic diseases: CT and MR imaging findings of differential diagnosis.

Neoplastic and nonneoplastic diseases may involve the liver with a regional distribution, which is defined as a non-focal process without any specific anatomic predilection. In this pictorial essay we...

Regional Distribution and Cell Type-Specific Subcellular Localization of Prothymosin Alpha in Brain.

Prothymosin alpha (ProTα) is an acidic nuclear protein implicated in several cellular functions including cell survival. ProTα is found in the central nervous system, but the regional and cell type-...

Worldwide Distribution of Type II Diabetes-Associated TCF7L2 SNPs: Evidence for Stratification in Europe.

Type II diabetes is a multifactorial disease with a complex etiology. Numerous genes have been implicated in disease pathogenesis. In particular, SNPs at the TCF7L2 locus have consistently shown stron...

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