Extravascular hemolysis

Intravascular hemolysis

Risk Factors

Surgical risk factors

Plavix

Plavix is a clot-busting drug, produced by Bristol-Myers Squibb Company, and reached annual sales in 2009 of $4.2m, making the third highest drug in the world (based on 2009 annual sales). Prescri...

Avoid hypotonic saline use in under-16s

Hypotonic saline solution should not be used for children aged 16 years or under...

Postoperative Hypotonic vs Isotonic Solutions in Kids

This F1000 commentary reports on a study whose findings support the use of isotonic solution postoperatively in children. Faculty of 1000

Trehangelins A, B and C, novel photo-oxidative hemolysis inhibitors produced by an endophytic actinomycete, Polymorphospora rubra K07-0510

VUmc discovers gene for HELLP syndrome

October 25, 2012 - The HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the mother.

New Data Highlighting Long-Term Efficacy and Safety Outcomes of PNH Patients Treated with Soliris® Reported at ASH Annual Meeting

Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN) today announced the presentation of new data demonstrating the long-term benefits of Soliris® (eculizumab) in patients with paroxysma...

Saving the Kidneys by Sparing Intravenous Chloride? Saving the Kidneys by Sparing Chloride

Intravenous fluid therapy is ubiquitous in modern medicine. The range of fluids available for intravenous administration represents a major advance from the early days of intravenous fluids in the 183...

Cavalcade of Risk #164

The latest edition of the Cavalcade of Risk examines Investment Risk, On-the-job Risk, Measurement Risk, Liability Risk, Risk of Inadequate Coverage, Risk of Working With Different Personalities and m...

Lifetime CVD Risk 'High' Even Without Risk Factors

Even in those with optimal risk factor profiles, the lifetime risk of developing heart disease tops 30%, new research suggests. Medscape Medical News

Isolation of Hemoglobin from Bovine Erythrocytes by Controlled Hemolysis in the Membrane Bioreactor.

In this work, we describe an optimized procedure based on gradual hemolysis for the isolation of hemoglobin derived from bovine slaughterhouse erythrocytes in a membrane bioreactor. The membrane biore...

Impact of hemolysis during sample collection: How different is drug concentration in hemolyzed plasma from that of normal plasma?

Hemolysis is a common phenomenon in clinical studies. Despite the growing interest in hemolysis matrix effect, how hemolysis impacts the representability of hemolyzed plasma samples was rarely evaluat...

An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches.

Percentage hemolysis in red cell concentrates (RCC) for transfusion is an indicator of RBC damage. As several factors need to be measured to determine hemolysis, and multiple assays are available for...

Thrombosis in patients with paroxysmal nocturnal hemoglobinuria.

Paroxysmal nocturnal hemoglobinuria is a disorder associated with hemolysis, pancytopenia, and thrombosis due to the loss of the glycosylphosphatidylinositol (GPI) anchored complement regulatory prote...

Cell-Cell Electrofusion: Optimization of Electric Field Amplitude and Hypotonic Treatment for Mouse Melanoma (B16-F1) and Chinese Hamster Ovary (CHO) Cells.

Efficient electroporation of cells in physical contact induces cell fusion, and this process is known as electrofusion. It has been shown that appropriate hypotonic treatment of cells before the appli...