Search Results for "S1p Htr8 Receptor"
Original Source: EFFECTS OF ADIPONECTIN ON HUMAN TROPHOBLAST INVASION.
Adiponectin is an adipokine with insulin-sensitizing, anti-inflammatory, anti-atherogenic, and anti-proliferative effects. The expression of specific adiponectin receptors in the placenta and in the endometrium suggests a role for this cytokine in placental development, but this role has not been yet elucidated. The invasion of trophoblast cells during the first trimester of pregnancy being crucial to placentation process, we have studied adiponectin effects on human trophoblat invasive capacities. We found...
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Metabotropic Glutamate Receptor 4 (mGluR4)
Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor famil...
Parathyroid Hormone PTH Receptor
There are two known parathyroid hormone receptors in mammals termed PTH1R and PTH2R. These receptors bind parathyroid hormone and are members of the GPCR family of transmembrane proteins. * parathy...
Interleukin 6 IL 6 Receptor IL 6R
Although the causes of rheumatoid arthritis are not fully understood, constitutive overproduction of interleukin-6 (IL-6), a multifunctional cytokine that regulates immune response, inflammatory react...
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Leiden researchers achieve highest resolution ever for human protein
Receptor The protein in question is the adenosine A2A receptor, the main receptor for caffeine in the human body. This receptor is also linked to Parkinson's disease. The class of around 800 protei...
Where have all the active receptor states gone?
Defining G protein–coupled receptor ligand efficacy and biased agonism in precise chemical terms is one challenge posed by the current structural data that exists for this receptor family. Concepts...
Breast Cancers Can Change Biologically as They Progress and Relapse
In many women with recurrent breast cancer, the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) status of their tumors changes between treatment...
Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect
(University of Colorado Denver) Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results...
T Cell Receptor Signaling Pathway in Oncology Drug Pipeline Update 2013
Extra value: One year of free online updates included with this product Stimulation of the T cell receptor leads to the activation of NFkB and NFAT signaling modules which play a key role in T cell re...
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Citation Eastabrook GDM, Hu Y, Tan R, Dutz JP, MacCalman CD, von Dadelszen P. Decidual NK cell-derived conditioned medium (dNK-CM) mediates VEGF-C secretion in extravillous cytotrophoblasts. Am J Repr...
The effects of human chorionic gonadotrophin, progesterone and oestradiol on trophoblast function.
Remodelling of the uterine vasculature during the first trimester of human pregnancy requires invasion of trophoblast from the placenta into decidual spiral arterioles. The pregnancy-associated hormon...
Physiological roles of the melanocortin MC(3) receptor.
The melanocortin MC(3) receptor remains the most enigmatic of the melanocortin receptors with regard to its physiological functions. The receptor is expressed both in the CNS and in multiple tissues i...
Self-Assembly of Dimeric Tetrathiafulvalene-Calix4pyrrole: Receptor for 1,3,5-Trinitrobenzene.
The synthesis and binding properties of a tetrathiafulvalene (TTF)-calix[4]pyrrole receptor 2 appended with one 3,5-dinitrobenzoate guest moiety are reported. The preliminary studies revealed that the...
Based on indications of direct physical interactions between neuropeptide and monoamine receptors in the early 1980s, the term receptor-receptor interactions was introduced and later on the term recep...