Sandhoff Disease Pages on BioPortfolio:

BioPortfolio - beta-Hexosaminidase alpha Chain
N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice. Sandhoff disease involves the CNS accumulation
...
http://www.bioportfolio.com/indepth/beta-Hexosaminidase_alph...

BioPortfolio.com - BioWeb Leukodystrophy Globoid Cell Search
TRENDS in Cell Biology GM1 gangliosidosis TayTH Sachs and Sandhoff disease Sandhoff disease Fabry disease Gaucher disease Metachromatic leukodystrophy ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=s...

BioPortfolio - Gangliosidosis Gm1
... Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ... Tay Sachs; Sandhoff, I-Cell, Sanfillipo, GM1 Gangliosidosis ...
http://www.bioportfolio.com/indepth/Gangliosidosis_Gm1.html...

BioPortfolio.com - BioWeb Gangliosidosis GM1 Search
Synonyms Gangliosidosis Beta Hexosaminidase B Defeciency Gangliosidosis GM2 Type 2 Disorder Subdivisions None General Discussion Sandhoff Disease is a rare ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=s...

BioPortfolio Biotechnology BioNews : live article
... Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease .... using LSD mouse models of Tay-Sachs disease, Sandhoff disease, ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=h...

Health Topics - Quest Diagnostics Patient Health Library
Salt and Meniere's Disease · SAM-e, Go to top of page Top. Sandhoff Disease · Santavuori Disease · Santavuori-Haltia Disease ...
http://www.bioportfolio.co.uk/cgi-bin/htm_hl.pl?DB=search&ST...

BioPortfolio Biotechnology BioNews : live article
These included beta-hexosaminodase HEXB, frequently mutated in the lysosomal storage disorder Sandhoff disease. We now report that the 5q13.3 breakpoint ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=h...

BioPortfolio "hexosaminidase B (beta polypeptide)" Antibody
p.143-151 TITLE: The X-ray crystal structure of human beta-hexosaminidase B provides new insights into Sandhoff disease AUTHOR: Maier, T; Strater, N; ...
http://www.bioportfolio.co.uk/antibody/hexosaminidase%20B%20...

Biotechnology, Pharmaceutical and Life Science Email addresses for ...
Individuals are categorized by their professional expertise (e.g. specific to a gene, disease, molecule or technique). You can specify the type of ...
http://www.bioportfolio.com/advertis/bioemail.htm...

BioPortfolio.com - BioWeb IC GREEN INDOCYANINE GREEN gravior ...
Sandhoff Disease - Quest Diagnostics Patient Health Library National Organization for Rare Disorders, Inc. 2001 Beacon Street Suite 204 Boston, ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?DB=se...

Results from other life science and pharmaceutical sites:

Sandhoff Disease Information Page: National Institute of ...
Sandhoff disease information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
http://www.ninds.nih.gov/disorders/sandhoff/sandhoff.htm...

OMIM - SANDHOFF DISEASE
MIM #268800 · Text · Description · Clinical Features · Heterogeneity · Diagnosis · Pathogenesis · Mapping · Molecular Genetics · Population Genetics ...
http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=268800...

Sandhoff disease - Genetics Home Reference
Sandhoff disease is a rare inherited disorder that causes progressive destruction of nerve cells in the brain and spinal cord (the central nervous
system). ...
http://ghr.nlm.nih.gov/condition=sandhoffdisease...

Stem cells act through multiple mechanisms to benefit mice with ...
Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Nature Genetics Article (01 Oct 1995) ...
http://www.nature.com/nm/journal/v13/n4/abs/nm1548.html...

Sandhoff disease heterozygote detection: a component of population ...
Serum and leukocyte hexosaminidase profiles (total activity and percent heat- labile activity levels) in obligate Sandhoff disease (SHD) heterozygotes differ
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=16...

Lysosomal Storage Disorders: Inherited Disorders of Metabolism ...
Tay-Sachs disease and Sandhoff's disease are sphingolipidoses caused by hexosaminidase deficiency that produces severe neurologic symptoms and early
death. ...
http://www.merck.com/mmpe/sec19/ch296/ch296f.html...

Sandhoff disease heterozygote detection: a component of population ...
Carrier frequencies for the allele(s) causing Sandhoff disease have been estimated for the U.S. Jewish and non-Jewish populations. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=16...

A case of combined Farber and Sandhoff disease. [Eur J Pediatr ...
We describe a patient with the biochemically established combination of Farber and Sandhoff disease. A 6-month-old girl of consanguineous Turkish parents ...
http://www.ncbi.nlm.nih.gov/pubmed/2744019...

Peripheral nervous system manifestations in a Sandhoff disease ...
Sandhoff disease is an inherited lysosomal storage disease caused by a mutation in the gene for the β-subunit (Hexb gene) of β-hexosaminidase A (αβ) and B ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=19...

Cardiac involvement in Sandhoff's disease. Inborn ...[Am J Cardiol ...
1973]; Studies in Tay-Sachs and Sandhoff's diseases. ... 1974]; Sandhoff's disease (GM 2 gangliosidosis type 2): clinical, chemical, and enzyme studies in
...
http://www.ncbi.nlm.nih.gov/pubmed/4835758...

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